Mr. Saverio Pietrantonio Profile

Saverio Pietrantonio

at Mannheim Institute for Intelligent Systems in Medicine

SPIE Involvement:

Author

Publications (1)

This will count as one of your downloads.

You will have access to both the presentation and article (if available).

DOWNLOAD NOW

This content is available for download via your institution's subscription. To access this item, please sign in to your personal account.

Email or Username Forgot your username?

Password Forgot your password?

Show

Keep me signed in

No SPIE account? Create an account

Proceedings Article | 16 October 2023 Paper

Towards a fast and accurate simulation framework for 3D spherical source localization in the near field of a coded aperture gamma camera

Tobias Meißner, Saverio Pietrantonio, Werner Nahm, Jürgen Hesser

Proceedings Volume 12627, 126270M (2023) https://doi.org/10.1117/12.2670883

KEYWORDS: Spherical lenses, Near field, Point spread functions, Voxels, Monte Carlo methods, Coded apertures, Cameras, Source localization, Device simulation, Collimators

Read Abstract +

Handheld gamma cameras with coded aperture collimators are under investigation for intraoperative imaging in nuclear medicine. Unlike other types of collimators, a coded aperture offers the possibility of 3D imaging of small spherical sources in the near field. However, due to the non-linear system model this option has rarely been investigated. We hypothesize that a deep learning approach is capable of 3D localization of spherical sources with an accuracy that is required for sentinel lymph node biopsy. In order to generate a sufficient amount of training data and densely sample the field of view Monte Carlo simulations are computationally too expensive. Thus, a fast and accurate simulation framework called ConvSim is presented. It computes the detector image from a 3D volume distribution of gamma sources in front of the gamma camera described as a voxel cube. By slice-wise convolutions with the corresponding point spread functions (PSF) a simulation time of few seconds is reached. For spherical sources non-linear near field effects are considered additionally. Comparing the generated detector images of exemplary spherical sources at different distances to Monte Carlo simulations yield a good correspondence with a multi-scale structural similarity index (MS-SSIM) between 0.65 and 0.91. Even though ConvSim entirely ignores the photon energy, the simulation framework serves as a fast and accurate alternative to time-consuming Monte Carlo simulations. For the future, the framework might be useful for investigating new types of coded apertures or the reconstruction of extended sources. ConvSim is available at https://github.com/tomeiss/convsim.

My Library

You currently do not have any folders to save your paper to! Create a new folder below.

Folder Name

Folder Description

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks. You are receiving this notice because your organization may not have SPIE eBooks access.*

*Shibboleth/Open Athens users─please sign in to access your institution's subscriptions.

To obtain this item, you may purchase the complete book in print or electronic format on SPIE.org.

ORGANIZATIONAL
Sign in with credentials provided by your organization.

Organizational Username

Organizational Password

Show/Hide Password

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members:

Non-members: ADD TO CART

Keywords/Phrases

Search In:

Publication Years