KEYWORDS: Monte Carlo methods, Diffuse optical tomography, Sensors, Near infrared spectroscopy, Spectroscopy, Oxygen, Injuries, Hybrid optics, Heart, Head
We present a simulation study on the design of a multi-modal high-density hybrid diffuse optical tomographic probe for monitoring infants with congenital heart disease (CHD) before, during, and after surgery. Different probe designs are evaluated based on the signal distribution and sensitivity profile generated using a Monte Carlo-based simulation toolbox. An optimal design was chosen after several iterations starting from the initial design. To cover a wide region of interest, this unit design was extended in a modular fashion, while respecting mechanical restrictions as well as the need for dense distribution of sources and detectors.
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