Mr. James R. Mansfield Profile

James R. Mansfield

Manager/Analysis Group at PerkinElmer Inc

SPIE Involvement:

Author | Instructor

SPIE Journal Paper | 1 September 2007 Open Access

Recent advances in catheter-based optical coherence tomography (OCT) have provided the necessary resolution and acquisition speed for high-quality intravascular imaging. Complications associated with clearing blood from the vessel of a living patient have

Matthew Bouchard, Sarah MacLaurin, Peter Dwyer, James Mansfield, Richard Levenson, Thomas Krucker

JBO, Vol. 12, Issue 05, 051601, (September 2007) https://doi.org/10.1117/12.10.1117/1.2799188

KEYWORDS: Luminescence, Skin, In vivo imaging, Multispectral imaging, Imaging systems, Molecular imaging, Signal detection, Data acquisition, Visible radiation, Drug discovery

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SPIE Journal Paper | 1 July 2005 Open Access

Autofluorescence removal, multiplexing, and automated analysis methods for in-vivo fluorescence imaging

James Mansfield, Kirk Gossage, Clifford Hoyt, Richard Levenson

JBO, Vol. 10, Issue 04, 041207, (July 2005) https://doi.org/10.1117/12.10.1117/1.2032458

KEYWORDS: Quantum dots, Luminescence, Multiplexing, Multispectral imaging, RGB color model, In vivo imaging, Skin, Imaging systems, Imaging spectroscopy, Tissues

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Proceedings Article | 8 August 2003 Paper

Use of hyperspectral imaging to profile cutaneous responses to bioweapons: a concept paper

Robert Gillies, Robin Levin, James Mansfield, Michael Hopmeier, Jenny Freeman

Proceedings Volume 5072, (2003) https://doi.org/10.1117/12.497946

KEYWORDS: Skin, Tissues, Hyperspectral imaging, Oxygen, Biological weapons, Chromophores, Imaging spectroscopy, Visualization, Absorption, Defense and security

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Proceedings Article | 27 March 2002 Paper

Visible hyperspectral imaging: monitoring the systemic effects of shock and resuscitation

Leopold Cancio, Derek Brand, Jeffery Kerby, Jenny Freeman, Michael Hopmeier, James Mansfield

Proceedings Volume 4614, (2002) https://doi.org/10.1117/12.460792

KEYWORDS: Skin, Oxygen, Tissues, Imaging systems, Hyperspectral imaging, Absorbance, Spectroscopy, Blood, Injuries, Blood circulation

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Proceedings Article | 22 February 2002 Paper

Infrared imaging of skin lesions

Laura McIntosh, James Mansfield, Michael Jackson, A. Neil Crowson, Henry Mantsch

Proceedings Volume 4577, (2002) https://doi.org/10.1117/12.455740

KEYWORDS: Skin, Tissues, Infrared imaging, Imaging spectroscopy, Spectroscopy, Infrared spectroscopy, Absorption, Data processing, Proteins, Collagen

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Proceedings Article | 17 May 2000 Paper

Classification of infrared spectra from skin tumors

Laura McIntosh, James Mansfield, A. Neil Crowson, John Toole, Henry Mantsch, Michael Jackson

Proceedings Volume 3907, (2000) https://doi.org/10.1117/12.386244

KEYWORDS: Skin, Tumors, Biopsy, Tissues, Spectroscopy, In vivo imaging, Photomicroscopy, Imaging spectroscopy, Skin cancer, Melanoma

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Proceedings Article | 14 March 2000 Paper

Development of visible and near-IR LCTF-based spectroscopic imaging systems for macroscopic samples

James Mansfield, Michael Sowa, Henry Mantsch

Proceedings Volume 3920, (2000) https://doi.org/10.1117/12.379588

KEYWORDS: Imaging spectroscopy, Spectroscopy, Visible radiation, Near infrared spectroscopy, Imaging systems, Reflectivity, Absorbance, RGB color model, Spectroscopes, Chromophores

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Proceedings Article | 15 July 1999 Paper

Near-infrared spectroscopic reflectance imaging: methods for functional imaging and in-vivo monitoring

James Mansfield, Michael Sowa, Henry Mantsch

Proceedings Volume 3597, (1999) https://doi.org/10.1117/12.356818

KEYWORDS: Imaging spectroscopy, Spectroscopy, Tissues, Reflectivity, Absorbance, Oxygen, Blood, Ischemia, Reflectance spectroscopy, Tissue optics

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Proceedings Article | 24 April 1998 Paper

Cancer diagnosis by infrared spectroscopy: methodological aspects

Michael Jackson, Keith Kim, John Tetteh, James Mansfield, Brion Dolenko, Raymond Somorjai, F. Orr, Peter Watson, Henry Mantsch

Proceedings Volume 3257, (1998) https://doi.org/10.1117/12.306098

KEYWORDS: Absorption, Tissues, Infrared radiation, Infrared spectroscopy, Proteins, Melanoma, Cancer, Spectroscopy, Breast, Receptors

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Proceedings Article | 24 April 1998 Paper

Assessment of tissue viability by near-IR spectroscopy and imaging

Michael Sowa, Jeri Payette, Miroslaw Stranc, Badr Abdulrauf, Mark Hewko, James Mansfield, Henry Mantsch

Proceedings Volume 3257, (1998) https://doi.org/10.1117/12.306084

KEYWORDS: Oxygen, Tissues, Surgery, Skin, Imaging spectroscopy, Absorption, Tissue optics, Reflectivity, Near infrared spectroscopy, Blood

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Proceedings Article | 24 April 1998 Paper

Hemodynamic information obtained by statistical analysis of near-IR spectroscopic images

Michael Sowa, Jeri Payette, Mark Hewko, James Mansfield, Henry Mantsch

Proceedings Volume 3257, (1998) https://doi.org/10.1117/12.306097

KEYWORDS: Multispectral imaging, Tissues, Reflectivity, Skin, Statistical analysis, Image segmentation, Principal component analysis, Absorption, Fuzzy logic, Hemodynamics

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Showing 5 of 11 publications

Course Instructor

SC693: Spectral Imaging for Biology and Medicine

The course will begin with a brief comparison between colorimetry and spectroscopy, outlining the differences between color vision and spectrally resolved sensing. It will then describe the variety of optical means that can be used to perform spectral imaging. Next, the core of the course will be an explanation of the variety of software analytical methods that must be used to extract useful and meaningful information from the spectral data sets. Finally, examples from a variety of applications will be presented, with opportunities for hands-on experience with relevant software tools.

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