This paper demonstrates the possibility of optically trapping a single calix[4]arene microcluster in water. Calix [4]arene microclusters with a size range between 2.53 to 2.84 µm were optically trapped using optical tweezers at 976 nm in water. The optical stiffness of trapped calix[4]arene microclusters was evaluated based on the trapping laser power density. The finding provides a starting point for possible optically controlled calixarene microcluster for sensor and actuator applications in water.
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