CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume PC12379 > Article
Presentation
9 March 2023 Understanding the biomechanical behaviors of the perilimbal sclera and aqueous veins during intraocular pressure regulation (Conference Presentation)
Guan Xu, Linyu Ni, Wonsuk Kim, Alexus Warchock, Erik Krawczyk, John Riesterer, Nikhil Gandikota, Sayoko Moroi, Alan Argento
Author Affiliations +
Proceedings Volume PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023; PC123791X (2023) https://doi.org/10.1117/12.2650393
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
Purposed at validating the hypothesis that overly stiff sclera undermines the passive and adaptive mechanisms of the aqueous outflow pathway in regulating IOP, we combined photoacoustic microscopy (PAM) and finite element analysis (FEA) technologies to resolve and quantify the strains in the aqueous veins and surrounding perilimbal sclera in human and porcine eyes at high resolution in 3D in our previous study. In this study, we introduced large dynamic range of scleral stiffness in intact porcine eyes by crosslinking and observed the correlations between the principal strains in sclera and aqueous veins during IOP elevations, and between the principal strains and the steady state IOP. The results showed strong correlations in both cases.
Conference Presentation
© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Guan Xu, Linyu Ni, Wonsuk Kim, Alexus Warchock, Erik Krawczyk, John Riesterer, Nikhil Gandikota, Sayoko Moroi, and Alan Argento "Understanding the biomechanical behaviors of the perilimbal sclera and aqueous veins during intraocular pressure regulation (Conference Presentation)", Proc. SPIE PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023, PC123791X (9 March 2023); https://doi.org/10.1117/12.2650393
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Sclera
Veins
Optical resolution
Photoacoustic microscopy
Finite element methods
Surgery
3D photoacoustic microscopy
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top