Mechanical properties of an artificial vascularized human skin

A. Passot; G. Cabodevila

doi:10.1117/12.886962

3 May 2011 Mechanical properties of an artificial vascularized human skin

A. Passot, G. Cabodevila

Author Affiliations +

Proceedings Volume 8068, Bioelectronics, Biomedical, and Bioinspired Systems V; and Nanotechnology V; 80680C (2011) https://doi.org/10.1117/12.886962
Event: SPIE Microtechnologies, 2011, Prague, Czech Republic

Abstract

In order to make blood sample tests an artificial skin similar to that of the baby's heel is modeled and realized. The most superficial bloodstream and the two main layers of the skin -epidermis and dermis- have to be recreated. Studies and capillaroscopies of the baby's heel give characteristics of these layers and the bloodstream. The skin is viscohyperelastic, but the choice of materials that will be used is based on the Young's modulus. The epidermis layer is based on a stronger less adhesive silicon rubber Elastosil. The dermis layer is composed of a mixture based on a very soft sticky silicon rubber Silgel and Sylgard. The mixture of Silgel with 5% Sylgard has an elastic modulus of 48 kPa which is similar to that of the dermis. The artificial skin is an assembly of several layers including a layer of Sylgard that is structured by a mold representing the capillary network and adapted to manufacturing processes in a clean room. Each layer is deposited by spin coating and is combined with the other through adhesion. Mechanical tests such as tension are performed to verify the mechanical properties of the artificial skin.

Citation Download Citation

A. Passot and G. Cabodevila "Mechanical properties of an artificial vascularized human skin", Proc. SPIE 8068, Bioelectronics, Biomedical, and Bioinspired Systems V; and Nanotechnology V, 80680C (3 May 2011); https://doi.org/10.1117/12.886962

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