In vivo detection of time-resolved singlet oxygen luminescence under PDT relevant conditions

Jan Schlothauer; Beate Röder; Steffen Hackbarth; Jürgen Lademann

doi:10.1117/12.839851

2 March 2010 In vivo detection of time-resolved singlet oxygen luminescence under PDT relevant conditions

Jan Schlothauer, Beate Röder, Steffen Hackbarth, Jürgen Lademann

Proceedings Volume 7551, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XIX; 755106 (2010) https://doi.org/10.1117/12.839851
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

For the fist time worldwide we report high amplitude NIR-Luminescence signals, measured in pig skin. The measurements are achieved with a recently developed setup that was shown to provide superior performance for ¹O₂- luminescence detection in vitro. This setup has been adapted to allow now the detection of singlet oxygen signals in vivo. Pig ears were used for first measurements as a widely accepted in vivo model for human skin.

Citation Download Citation

Jan Schlothauer, Beate Röder, Steffen Hackbarth, and Jürgen Lademann "In vivo detection of time-resolved singlet oxygen luminescence under PDT relevant conditions", Proc. SPIE 7551, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XIX, 755106 (2 March 2010); https://doi.org/10.1117/12.839851

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