Wide microfluidic channel used in suspension biochip detection system

Guoxiong Xu; Xi Zhang; Xuxiang Ni; Zukang Lu; Xiangqun Cao

doi:10.1117/12.710920

27 October 2006 Wide microfluidic channel used in suspension biochip detection system

Guoxiong Xu, Xi Zhang, Xuxiang Ni, Zukang Lu, Xiangqun Cao

Proceedings Volume 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine; 604733 (2006) https://doi.org/10.1117/12.710920
Event: Fourth International Conference on Photonics and Imaging in Biology and Medicine, 2005, Tianjin, China

Abstract

In this paper we describe a new kind of micro fluidic channel used in suspension biochip detection system suitable to area test of the sample that is different from cytometry, which has been fabricated by us. Cytometry is a conventional platform used in suspension biochip technology. At first, our detection system employs a widen micro fluidic channel width of lmm and different depth 50μ, 1OOμ,which is suitable to different size sample flow in the channel instead of the thin pipe used in the cytometry. Secondly suspension array is analyzed by CCD imaging technology in parallel in stead of detection micro beads or protein one by one. The wide micro channels have been fabricated by three ways: laser ablation, chemical etching and mechanical method. The stability of the micro field is a key factor of the biochip detection system when sample flows through the wide micro channel. A novel sample control method to keep the suspension microspheres flow stably throw the test area has been presented.

Citation Download Citation

Guoxiong Xu, Xi Zhang, Xuxiang Ni, Zukang Lu, and Xiangqun Cao "Wide microfluidic channel used in suspension biochip detection system", Proc. SPIE 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine, 604733 (27 October 2006); https://doi.org/10.1117/12.710920

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KEYWORDS

Microfluidics

Luminescence

Chemical elements

Imaging systems

Liquids

Molecules

Charge-coupled devices

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