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Cerebral blood flow (CBF) monitoring is crucial during cerebrovascular surgery to inform decision making. In cerebral aneurysm clipping cases, CBF monitoring is routinely used to confirm patency in vessels and determine successful aneurysmal obliteration. Current intraoperative tools for CBF monitoring such as indocyanine green angiography (ICGA) do not provide real-time and continuous assessment of CBF.
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David R. Miller, Ramsey Ashour, Colin T. Sullender, Andrew K. Dunn, "Intraoperative real-time and continuous cerebral blood flow visualization with laser speckle contrast imaging," Proc. SPIE 11945, Clinical and Translational Neurophotonics 2022, 1194502 (4 March 2022); https://doi.org/10.1117/12.2608914