Energy weighted imaging of sub pixel contamination in pharmaceutical hard capsule with CdZnTe Timepix3

Julian Fey; Michael Schuetz; Simon Procz; Sebastian Useche; Michael Fiederle

doi:10.1117/12.2596375

1 August 2021 Energy weighted imaging of sub pixel contamination in pharmaceutical hard capsule with CdZnTe Timepix3

Julian Fey, Michael Schuetz, Simon Procz, Sebastian Useche, Michael Fiederle

Proceedings Volume 11838, Hard X-Ray, Gamma-Ray, and Neutron Detector Physics XXIII; 118380Y (2021) https://doi.org/10.1117/12.2596375
Event: SPIE Optical Engineering + Applications, 2021, San Diego, California, United States

Abstract

This work investigates the capabilities of a state-of-the-art photon counting CdZnTe Timepix3 detector by combining sub-pixel resolution and energy weighted imaging to resolve and identify metallic particles (< 35 µm) in contaminated pharmaceutical hard capsules. While previous pixelated photon counting semiconductor detectors such as the Timepix or Medipix3 allowed single event analysis only for low photon fluxes that are rather unsuitable for imaging purposes, the new Timepix3 detector allows for the analysis of single events even at high X-ray fluxes due to its data driven data output. The challenges of the project like sufficient charge collection and processing of larger data sets for sub-pixel imaging, the influence of charge sharing and X-ray fluorescence on the spatial and energy resolution as well as 3 different approaches of the energy weighted identification of the metallic powders will be discussed.

Conference Presentation

Citation Download Citation

Julian Fey, Michael Schuetz, Simon Procz, Sebastian Useche, and Michael Fiederle "Energy weighted imaging of sub pixel contamination in pharmaceutical hard capsule with CdZnTe Timepix3", Proc. SPIE 11838, Hard X-Ray, Gamma-Ray, and Neutron Detector Physics XXIII, 118380Y (1 August 2021); https://doi.org/10.1117/12.2596375

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