TEK-Momentum is the Business Innovation and Technology Department in the Faculty of Engineering at the University
of Southern Denmark in Odense. Since its establishment in 2010 the Department has adopted an exploratory technology
transfer, open business development and co-creation strategy that goes beyond traditional technology transfer activities.
This is an emerging strategy that has been shaped for the last 5 years even before the formal establishment of TEKMomentum.
It emerged out of multiple dialog-based interactions with small- and medium-sized companies by focusing
on matching real life problems with potential problem solvers. The main priority of such strategy is maximizing the
value of the potential contributions from the multiple stakeholders and not on the technology development issues per se.
In this paper we will present an overview of TEK-Momentum's approach by using as case studies two recent successful
projects. The first one focuses on the commercialization of an LED illumination system. The second one focuses on the
commercialization of an optical ring resonator-based temperature sensor.
Academic spin-offs are an important mechanism to develop the regional economy and support their parent institutions.
This research applies the lessons learned from an action research project focusing on the development of a model and 10
hypotheses that examine university spin-off efficiency. The formation of the academic spin-off is conceptualized to be
embedded in a collective that includes entrepreneurs and those who help them transform their ideas into ventures. Ten
factors organized into two constructs - idea-venture path and collective structure, are identified as determinants of
academic spin-off efficiency.
We apply a previously developed 3D Finite-Difference Time-Domain (FDTD) simulation method to model the optical
phase contrast microscopic (OPCM) visualization of Gold nanoparticles (NPs) attached to the nucleus of a singe
biological cell. We consider a realistic size 3D cell model at optical immersion conditions, i.e. when the refractive index
values of the cytoplasm and of the extra-cellular medium are equal. The visual effect of the Gold NPs is studied at both
resonant and non-resonant conditions. The results show that, at resonance, there are specific visual patterns that could be
used for the identification of the presence of NPs at the nucleus' surface. The model demonstrates the capability to model
the specific conditions of OPCM image enhancement by optically controlling the resonant properties of the NPs.
The Finite-Difference Time-Domain (FDTD) modeling technique is applied to build a simple simulation equivalent of
an optical phase contrast microscope. The model is validated by demonstrating the effect of optical immersion on the
optical phase contrast microscope image of a simple biological cell containing a cytoplasm, a nucleus and a membrane.
To the best of our knowledge, this is the first study using the FDTD approach to construct optical phase contrast
microscope images. The results demonstrate the potential of the FDTD modelling approach and extend its area of
applicability a new biomedical research area.
The Finite-Difference Time-Domain (FDTD) approach is applied to model optical phase contrast microscope (OPCM)
imaging of Gold nanoparticles (NPs) in singe biological cells. We first demonstrate the effect of optical clearing on the
optical phase contrast microscope image of a realistic size biological cell containing a cytoplasm, a nucleus and a
membrane. The FDTD-based OPCM model is then applied to visualize the presence of a cluster of Gold NPs in the
cytoplasm at optical conditions. To the best of our knowledge, this is the first study using the FDTD approach in
combination with Fourier optics techniques to construct OPCM images of realistic size cells containing NPs. The results
demonstrate the potential of the FDTD modelling approach and extend its area of applicability into a new biomedical research area.
A solid education in optical devices and optical communication systems must include an understanding of the basic building blocks of optical devices and networks as well as the interplay between them. Software vendors, such as Optiwave Systems Inc., provide free as well as for-purchase software tools that can be used in classroom and computer labs as an educational aid. This paper examines the role software simulation tools play in the education of students studying optical communication and related disciplines. The different techniques to employ photonic simulation software in classroom lectures, computer labs and graduate research are discussed.
This article represents an initial step in the development of a research methodology that will be applied later to study
open source innovation practices in company projects where the released technology or asset is other than software code.
A brief review of four possible analytical approaches is presented based on the research literature on open innovation,
horizontal user innovation networks, business ecosystems and value creation and appropriation. The OpenAccess project
of the Silicon Integration Initiative (Si2) is considered as a potential case study of non-software open source project.
In this article we examine how (i) company type and (ii) the competitive intelligence information used by small
technology-based companies affect their innovation performance. The focus is on the specific information types used and
not on the information sources. Information topics are classified in four groups - customers (10), company (9),
competitor (11) and industry (12). The sample consists of 45 small new technology-based companies, specialized
suppliers, and service companies from a variety of sectors - software, photonics, telecommunications, biomedical
engineering and biotech, traditional manufacturing etc. The results suggest that the total number of intelligence
information topics companies use to make decisions about innovation is not associated with the number of their new
products, processes, services and patents. Therefore the companies in our sample do not seem to have the resources,
processes or value systems required to use different competitive intelligence information when making decisions on
innovation or may rely more on their own internal logic than on external information. Companies are classified using a
Pavitt-like taxonomy. Service companies are considered as a separate company type. This allows for explicitly studying
both, the innovative role of new services in product driven companies, and the role of new product development in
service companies.
Pilot results on the application of the finite-difference time-domain (FDTD) approach for studying the implementation of the optical immersion technique for the visualization of single and multiple gold nanoparticles in biological cells are presented. We focus on two different scenarios considering single biological cells containing (1) cytoplasm, nucleus, and membrane and (2) cytoplasm, nucleus, gold nanoparticles, and membrane. To the best of our knowledge, this is the first time the cell membrane thickness and gold nanoparticle effects on the forward scattered light from biological cells are discussed. The applicability and the potential of the FDTD approach for studying optical immersion technique enhanced bioimaging is demonstrated.
The FDTD modeling technique is applied to provide additional insight on the effect of the cell membrane thickness in optical immersion enhanced phase contrast microscope imaging. Pilot results on the application of the FDTD approach for studying the implementation of the optical immersion technique for the visualization of single and multiple gold nanoparticles in biological cells are also presented. The paper focuses on three different scenarios considering single biological cells containing i) cytoplasm and membrane, ii) cytoplasm, nucleus and membrane, and iii) cytoplasm, nucleus, gold nanoparticle(s) and membrane. To the best knowledge of authors, this is the first research study discussing the cell membrane thickness and single gold nanoparticle effects on the forward scattered light from biological cells. The potential of the FDTD approach and its applicability to new and promising biomedical optics research areas such as the study of optical immersion technique enhanced bio-imaging is demonstrated.
Biological cells can be considered as dielectric objects with a given refractive index distribution. Light scattering simulations provide us with an efficient tool for studying cell morphology as well as the nature of scattering and its sources. The analysis of this information is the basis for a better understanding and development of new optical methods for non-invasive biomedical diagnostics. Here we demonstrate the potential of Finite-Difference Time-Domain (FDTD) method based software tools for the simulation of light scattering from single cells in situations where other approaches simply do not work or the approximations inherited in them begin to be questionable.
In the present paper we review the state of the art of two complementary propagation techniques with applications for integrated optics device modeling: the Finite-Difference Time-Domain and the Beam Propagation Method. In both cases we focus on their main features such as the types of propagation schemes and the material effects that can be modeled. In addition, we also consider a 2D mode solver based on a complex root finding procedure - a representative mode solving technique that is of significant interest for design and modeling of leaky mode based devices. Each of the methods is illustrated with appropriate simulation examples of devices and waveguide structures being of current research interest: photonic band gap structures, waveguide gratings, ARROW waveguides etc. The selected examples show the power of the methods as well as the consistency and the complementarity of their results when applied together.
This presentation will emphasize the current status of advanced design and simulation tools in photonics technology. The focus will be on Wavelength Division Multiplexing (WDM) component and integrated optic circuits modeling, although some aspects of optical link simulations will also be discussed. A wide variety of numerical methods such as the Beam Propagation Method (BPM), the Coupled Mode Theory (CMT), the Transfer Matrix Method (TMM), and the Finite-Difference Time Domain Method (FDTDM) in their state-of-the-art implementation will be presented. The results from simulating selected photonic components will be discussed.
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