Dr. Sri Rama Pranav Kumar Lanka Profile

Dr. Sri Rama Pranav Kumar Lanka

Research Fellow at Tyndall National Institute

SPIE Involvement:

Author

Publications (24)

Proceedings Article | 17 October 2023 Paper

A virtual comparison of different time-of-flight-based diffuse optical spectroscopic techniques

Pranav Lanka, Marcelo Saito Nogueira, Vanessa R. Rodrigues, Shree Krishnamoorthy, Katarzyna Komolibus, Rekha Gautam, Stefan Andersson-Engels, Sanathana Konugolu Venkata Sekar

Proceedings Volume 12628, 126282L (2023) https://doi.org/10.1117/12.2671008

KEYWORDS: Spectroscopy, Optical spectroscopy, Tissues, Optical properties, Matrices, Interferometry, Background noise

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SPIE Journal Paper | 3 April 2023 Open Access

Interstitial null-distance time-domain diffuse optical spectroscopy using a superconducting nanowire detector

Vamshi Damagatla, Pranav Lanka, Annalisa Brodu, Niels Noordzij, Jessie Qin-Dregely, Andrea Farina, Antonio Pifferi

JBO, Vol. 28, Issue 12, 121202, (April 2023) https://doi.org/10.1117/12.10.1117/1.JBO.28.12.121202

KEYWORDS: Photons, Simulations, Absorption, Diffuse optical spectroscopy, Light absorption, Scattering, Liquids, Superconductors, Signal detection, Nanowires

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SignificanceInterstitial fiber-based spectroscopy is gaining interest for real-time in vivo optical biopsies, endoscopic interventions, and local monitoring of therapy. Different from other photonics approaches, time-domain diffuse optical spectroscopy (TD-DOS) can probe the tissue at a few cm distance from the fiber tip and disentangle absorption from the scattering properties. Nevertheless, the signal detected at a short distance from the source is strongly dominated by the photons arriving early at the detector, thus hampering the possibility of resolving late photons, which are rich in information about depth and absorption.AimTo fully benefit from the null-distance approach, a detector with an extremely high dynamic range is required to effectively collect the late photons; the goal of our paper is to test its feasibility to perform TD-DOS measurements at null source–detector separations (NSDS).ApproachIn particular, we demonstrate the use of a superconducting nanowire single photon detector (SNSPD) to perform TD-DOS at almost NSDS ( ≈ 150 μm ) by exploiting the high dynamic range and temporal resolution of the SNSPD to extract late arriving, deep-traveling photons from the burst of early photons.ResultsThis approach was demonstrated both on Monte Carlo simulations and on phantom measurements, achieving an accuracy in the retrieval of the water spectrum of better than 15%, spanning almost two decades of absorption change in the 700- to 1100-nm range. Additionally, we show that, for interstitial measurements at null source–detector distance, the scattering coefficient has a negligible effect on late photons, easing the retrieval of the absorption coefficient.ConclusionsUtilizing the SNSPD, broadband TD-DOS measurements were performed to successfully retrieve the absorption spectra of the liquid phantoms. Although the SNSPD has certain drawbacks for use in a clinical system, it is an emerging field with research progressing rapidly, and this makes the SNSPD a viable option and a good solution for future research in needle guided time-domain interstitial fiber spectroscopy.

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SPIE Journal Paper | 11 March 2023 Open Access

Solid optical tissue phantom tools based on upconverting nanoparticles for biomedical applications

Gokhan Dumlupinar, Sanathana Konugolu Venkata Sekar, Claudia Nunzia Guadagno, Jean S. Matias, Pranav Lanka, Chris K.W. Kho, Stefan Andersson-Engels

JBO, Vol. 28, Issue 03, 036004, (March 2023) https://doi.org/10.1117/12.10.1117/1.JBO.28.3.036004

KEYWORDS: Tissues, Biomedical optics, Solids, Tissue optics, Nanoparticles, Scattering, Optical properties, Biophotonic applications, Silicon, Deep tissue imaging

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Proceedings Article | 7 March 2023 Presentation + Paper

Superconducting nanowire detector for interstitial null-separation time-domain diffuse optical spectroscopy

Vamshi Damagatla, Pranav Lanka, Andrea Farina, Annalisa Brodu, Niels Noordzijc, Jessie Qin-Dregely, Antonio Pifferi

Proceedings Volume 12376, 123760F (2023) https://doi.org/10.1117/12.2649028

KEYWORDS: Photons, Monte Carlo methods, Absorption, Superconductors, Nanowires, Simulations, Diffuse optical spectroscopy, Silicon photomultipliers, Scattering

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Proceedings Article | 6 March 2023 Presentation

A solid optical phantom recipe and tools based on upconverting nanoparticles for biomedical applications

Sanathana Konugolu-Venkata-Sekar, Gokhan Dumlupinar, Claudia Nunzia Guadagno, Jean Matias, Pranav Lanka, Chris K. W. Kho, Stefan Andresson-Engels

Proceedings Volume PC12370, PC123700C (2023) https://doi.org/10.1117/12.2650114

KEYWORDS: Biomedical optics, Solids, Nanoparticles, Optical phantoms, Biophotonic applications, Manufacturing, Upconversion, Scattering, Optical properties, Deep tissue imaging

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Proceedings Article | 6 March 2023 Presentation

GASMAS for the non-invasive monitoring of oxygen gas in healthy neonates

Sri Rama Pranav Kumar Lanka, Jurate Panaviene, Konstantin Grygoryev, Sanathana Konugolu Venkata Sekar, Eugene Dempsey, Stefan Anderresson-Engels

Proceedings Volume PC12368, PC123680N (2023) https://doi.org/10.1117/12.2651130

KEYWORDS: Oxygen, Lung, Scattering media, Chest, Absorption spectroscopy

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SPIE Journal Paper | 15 June 2022 Open Access

Multi-laboratory performance assessment of diffuse optics instruments: the BitMap exercise

Pranav Lanka, Lin Yang, David Orive-Miguel, Joshua Deepak Veesa, Susanna Tagliabue, Aleh Sudakou, Saeed Samaei, Mario Forcione, Zuzana Kovacsova, Anurag Behera, Thomas Gladytz, Dirk Grosenick, Lionel Hervé, Turgut Durduran, Karolina Bejm, Magdalena Morawiec, Michał Kacprzak, Piotr Sawosz, Anna Gerega, Adam Liebert, Antonio Belli, Ilias Tachtsidis, Frédéric Lange, Gemma Bale, Luca Baratelli, Sylvain Gioux, Alexander Kalyanov, Martin Wolf, Sanathana Konugolu-Venkata-Sekar, Marta Zanoletti, Ileana Pirovano, Michele Lacerenza, Lina Qiu, Edoardo Ferocino, Giulia Maffeis, Caterina Amendola, Lorenzo Colombo, Lorenzo Frabasile, Pietro Levoni, Mauro Buttafava, Marco Renna, Laura Di Sieno, Rebecca Re, Andrea Farina, Lorenzo Spinelli, Alberto Dalla Mora, Davide Contini, Paola Taroni, Alberto Tosi, Alessandro Torricelli, Hamid Dehghani, Heidrun Wabnitz, Antonio Pifferi

JBO, Vol. 27, Issue 07, 074716, (June 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.7.074716

KEYWORDS: Raster graphics, Optical properties, Diffuse optical imaging, Scattering, Imaging spectroscopy, Absorption, Tissue optics, Spectroscopes, Sensors, Oximetry

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SPIE Journal Paper | 2 February 2022 Open Access

Reproducibility of identical solid phantoms

Fangzhou Zhao, Pietro Levoni, Lorenzo Frabasile, Hong Qi, Michele Lacerenza, Pranav Lanka, Alessandro Torricelli, Antonio Pifferi, Rinaldo Cubeddu, Lorenzo Spinelli

JBO, Vol. 27, Issue 07, 074713, (February 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.7.074713

KEYWORDS: Scattering, Silicon, Absorption, Solids, Optical properties, Picosecond phenomena, Near infrared spectroscopy, Epoxies, Diffuse optical imaging, Visible radiation

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Proceedings Article | 9 December 2021 Paper

Phantoms for performance verification and quality control in developing a photonics-based medical device (VASCOVID): a regulatory driven approach

Sanathana Konugolu Venkata Sekar, Claudia Nunzia Guadagno, Marta Zanoletti, Lorenzo Cortese, Marco Pagliazzi, Pranav Lanka, Rainer Rothe Munoz, Eduardo Garrido, Talyta Carteano, Michele Lacerenza, Mauro Buttafava, Shahrzad Parsa, Udo Weigel, Alessandro Torricelli, Antonio Pifferi, Davide Contini, Turgut Durduran, Stefan Andersson-Engels

Proceedings Volume 11920, 119201Q (2021) https://doi.org/10.1117/12.2615398

KEYWORDS: Control systems, Manufacturing, Biomedical optics, Standards development, Solids, Liquids, Surveillance, Medical device development, Photonic devices, Optics manufacturing

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Proceedings Article | 5 March 2021 Presentation

A standardized approach to validate solid phantom recipes for 3D anthropomorphic phantoms in biophotonics

Sanathana Konugolu Venkata Sekar, Treasa Jiang, Pranav Lanka, Claudia Nunzia Guadagno, Andrea Pacheco, Antonio Pifferi, Stefan Andersson-Engels

Proceedings Volume 11633, 1163307 (2021) https://doi.org/10.1117/12.2579257

KEYWORDS: Biophotonic applications, 3D imaging standards, Solids, Tissue optics, Optical properties, Standards development, Tissues, Spectroscopy, Scattering

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Proceedings Article | 5 March 2021 Presentation + Paper

Investigating the lung using time-resolved diffuse optics

Antonio Pifferi, Andrea Farina, Alberto Dalla Mora, Pranav Lanka, Sanathana Konugolu Venkata Sekar, Massimo Miniati, Paola Taroni

Proceedings Volume 11639, 116390M (2021) https://doi.org/10.1117/12.2578858

KEYWORDS: Lung, Diffuse optical imaging, Signal detection, Optical properties, Monte Carlo methods, Chest, Silicon photomultipliers, Sensors, Pulsed laser operation, Physiology

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Proceedings Article | 5 March 2021 Presentation + Paper

Speckle fluctuations in time-domain diffuse optics

Lorenzo Colombo, Saeed Samaei, Pranav Lanka, Daniele Ancora, Marco Pagliazzi, Turgut Durduran, Piotr Sawosz, Adam Liebert, Antonio Pifferi

Proceedings Volume 11641, 116410J (2021) https://doi.org/10.1117/12.2577622

KEYWORDS: Speckle, Diffuse optical imaging, Tissue optics, Tissues, Spectroscopy, Speckle pattern, Scattering, Optical properties, Near infrared, Mode locking

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Proceedings Article | 5 March 2021 Presentation + Paper

Broadband optical spectroscopy of the human adipose and muscle tissues: an in-vivo pilot study

Sri Rama Pranav Kumar Lanka, A. Segala, Andrea Farina, Paola Taroni, A. Valerio, E. Nisoli, Rinaldo Cubeddu, Antonio Pifferi

Proceedings Volume 11639, 116390I (2021) https://doi.org/10.1117/12.2578276

KEYWORDS: Tissues, In vivo imaging, Optical spectroscopy, Optical properties, Diffuse optical spectroscopy, Tissue optics, Spectroscopy, Oximetry, Near infrared

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Proceedings Article | 5 March 2021 Presentation + Paper

A multi-laboratory comparison of photon migration instruments and their performances: the BitMap exercise

Sri Rama Pranav Kumar Lanka, Lin Yang, David Orive-Miguel, Joshua Deepak Veesa, Susanna Tagliabue, Aleh Sudakou, Saeed Samaei, Mario Forcione, Zuzana Kovacsova, Anurag Behera, Thomas Gladytz, Dirk Grosenick, Lionel Hervé, Giuseppe Lo Presti, Lorenzo Cortese, Turgut Durduran, Karolina Bejm, Magdalena Morawiec, Piotr Sawosz, Michal Kacprzak, Anna Gerega, Adam Liebert, Antonio Belli, Ilias Tachtsidis, Frédéric Lange, Gemma Bale, Luca Baratelli, Sylvain Gioux, Alexander Kalyanov, Martin Wolf, Sanathana Konugolu Venkata Sekar, Marta Zanoletti, Ileana Pirovano, Michele Lacerenza, Lina Qiu, Edoardo Ferocino, Giulia Maffeis, Caterina Amendola, Lorenzo Colombo, Mauro Buttafava, Marco Renna, Laura Di Sieno, Rebecca Re, Andrea Farina, Lorenzo Spinelli, Alberto Dalla Mora, Davide Contini, Alessandro Torricelli, Alberto Tosi, Paola Taroni, Hamid Dehghani, Heidrun Wabnitz, Antonio Pifferi

Proceedings Volume 11639, 116390F (2021) https://doi.org/10.1117/12.2578521

KEYWORDS: Raster graphics, Photonic devices, Tissue optics, Spectroscopes, Oximetry, Optical components, Mammography, Imaging spectroscopy, Functional imaging

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Proceedings Article | 2 March 2020 Presentation + Paper

Key features in the optical properties of tissue during and after radiofrequency ablation

Francis Kalloor Joseph, Pranav Lanka, Hindrik Kruit, Sanathana Konugolu Venkata Sekar, Andrea Farina, Rinaldo Cubeddu, Srirang Manohar, Antonio Pifferi

Proceedings Volume 11216, 112160H (2020) https://doi.org/10.1117/12.2546042

KEYWORDS: Tissue optics, Optical properties, Radiofrequency ablation, Tissues, Absorption, Scattering, Liver, Electrodes, Biomedical optics, Radio optics

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Proceedings Article | 22 July 2019 Paper

Solid heterogeneous phantoms for multimodal ultrasound and diffuse optical imaging: an outcome of the SOLUS project for standardization

Laura Di Sieno, Rinaldo Cubeddu, Hélène Sportouche, David Savéry, Sanathana Konugolu Venkata Sekar, Bogdan Rosinski, Andrea Farina, Edoardo Ferocino, Pranav Lanka, Paola Taroni, Antonio Pifferi, Alberto Dalla Mora

Proceedings Volume 11075, 1107516 (2019) https://doi.org/10.1117/12.2526645

KEYWORDS: Ultrasonography, Optical properties, Diffuse optical imaging, Silicon, Imaging systems, Solids, Multimodal imaging, Tissues, Absorption, Calibration

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