Dr. Mihaela Antonina Calin Profile

Dr. Mihaela Antonina Calin

at INOE

SPIE Involvement:

Author

Publications (8)

Proceedings Article | 13 August 2018 Paper

Applications of fractional wavelet-based denoising method in biomedical hyperspectral imaging

D. Manea, Mihaela Antonina Calin, Radu Mutihac

Proceedings Volume 10677, 106773O (2018) https://doi.org/10.1117/12.2319265

KEYWORDS: Wavelets, Hyperspectral imaging, Wavelet transforms, Denoising, Liver, Statistical analysis, Cameras, Biomedical optics, Hyperspectral systems, Charge-coupled devices

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Hyperspectral imaging is an optical technique that recently started being used in medical field. The correct extraction of spectral and spatial information from hyperspectral images depends on preprocessing, processing and analysis methods applied for an accurate diagnosis and monitoring medical treatments. A fundamental task in preprocessing hyperspectral images is the elimination of various types of noise generated by the hyperspectral systems. One of the major causes for the noise in a hyperspectral system is dark current noise. This type of noise arises from the temperature difference between environment and charge-coupled device of the hyperspectral camera. Electrons are generated over time and they are independent of the light falling on the detector. These electrons are captured by the potential wells of the charge-coupled device and counted as signal. The dark current noise removal can lead to an improvement in the performance of classification, target detection, anomaly detection and mapping methods, thus contributing to a better and more accurate diagnosis. Two denoising techniques - principal component analysis and minimum noise fractions were used until now in medical hyperspectral imaging applications. In this paper, the wavelet transform was proposed as a denoising technique for medical applications. The study was performed in both laboratory and clinical conditions. Two hyperspectral systems were used for the hyperspectral images acquisition of rabbit liver and a burn wound located on the posterior side of the patient left leg respectively using the same pushbroom hyperspectral camera but with two different scanning components (translation table and scanning mirror). The pushbroom hyperspectral camera acquires the image collecting the x-axis and λ information completely at the same time for a line on the y-axis. The two scanning components are used to move the sample (liver or patient leg) across the field of view of the hyperspectral camera so that the images are acquired line by line. The experimental results showed that the proposed denoising technique achieves better performance when applied to hyperspectral images acquired under laboratory conditions than in clinical situations. In conclusion, the wavelet transform could be considered a successful approach to denoising in laboratory hyperspectral measurements.

SPIE Journal Paper | 31 May 2017 Open Access

Simulated altitude exposure assessment by hyperspectral imaging

Mihaela Antonina Calin, Adrian Macovei, Sorin Miclos, Sorin Viorel Parasca, Roxana Savastru, Razvan Hristea

JBO, Vol. 22, Issue 05, 056012, (May 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.5.056012

KEYWORDS: Hyperspectral imaging, Hypoxia, Hyperspectral simulation, Oxygen, Medicine, Blood, Spectral models, Line scan image sensors, Oximetry, Skin

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SPIE Journal Paper | 13 April 2015 Open Access

Hyperspectral imaging-based wound analysis using mixture-tuned matched filtering classification method

Mihaela-Antonina Calin, Toma Coman, Sorin Viorel Parasca, Nicolae Bercaru, Roxana Savastru, Dragos Manea

JBO, Vol. 20, Issue 04, 046004, (April 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.4.046004

KEYWORDS: Tissues, Hyperspectral imaging, Skin, Image filtering, Image classification, Optical filters, Wound healing, Biological research, Natural surfaces, Imaging systems

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Proceedings Article | 13 July 2007 Paper

Mechanisms in photodynamic therapy: photosensitizers and cellular localization on K562 cells

Rodica-Mariana Ion, Monica Neagu, Gina Manda, Carolina Constantin, Mihaela Calin

Proceedings Volume 6632, 66320Q (2007) https://doi.org/10.1117/12.727968

KEYWORDS: Photodynamic therapy, Luminescence, Control systems, Tumors, Cell death, Tissue optics, Helium neon lasers, Oxygen, Absorption, Microscopes

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Proceedings Article | 2 July 1998 Paper

Fluid optical components and their applications in optoelectronics

Roxana Radvan, Mihaela Calin, Roxana Savastru, Maria Robu, Mihaela Radu

Proceedings Volume 3405, (1998) https://doi.org/10.1117/12.312666

KEYWORDS: Liquids, Optical components, Glasses, Optoelectronics, Optical calibration, Lenses, Temperature metrology, Absorbance, Nickel, Copper

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Proceedings Article | 2 July 1998 Paper

Comparative study of the thermal effects generated by laser irradiation for medical applications

Mihaela Calin, M. Tomescu, Roxana Radvan, Mihaela Radu, Teodor Necsoiu

Proceedings Volume 3405, (1998) https://doi.org/10.1117/12.312655

KEYWORDS: Thermal effects, Laser irradiation, Semiconductor lasers, Tissues, Argon ion lasers, Thermography, Image processing, Algorithm development, Laser tissue interaction, Laser therapeutics

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Proceedings Article | 2 July 1998 Paper

Optical properties of polycrystalline InxGa1-xSb (x=0.20) from 15 to 30 um

Cristiana Grigorescu, Stefan Manea, Michaela Logofatu, Ion Munteanu, B. Logofatu, Mihaela Calin, Mihaela Radu, Mihail Lazarescu

Proceedings Volume 3405, (1998) https://doi.org/10.1117/12.312676

KEYWORDS: Absorption, Optical properties, Temperature metrology, Reflectivity, Crystals, Gallium antimonide, Optoelectronics, Spectrophotometry, Semiconductors, Binary data

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Proceedings Article | 2 July 1998 Paper

Photodynamic therapy using hematoporphyrin derivative and He-Ne laser irradiation in Erlich tumor: an experimental study on mice

Mihaela Radu, D. Ciotaru, Mihaela Calin, G. Savi, M. Bota, Carmen Stroila

Proceedings Volume 3405, (1998) https://doi.org/10.1117/12.312654

KEYWORDS: Tumors, Luminescence, Helium neon lasers, Photodynamic therapy, Microscopy, Absorption, In vivo imaging, In vitro testing, Visible radiation, Absorption spectroscopy

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