New spatial domain (SD) frequency modulation imaging (SPIFI) architectures are developed that enable the use of the full numerical aperture of long working distance excitation optics without sacrificing the field-of-view. When multiplexed with wavelength domain (WD) SPIFI, multiple advantages follow. One, the WD-SPIFI signals can be used to optimize the multiphoton SD-SPIFI signals. Two, these new SD-SPIFI architectures enable video rate SPIFI. Finally, applications of these new architectures to advanced manufacturing will be presented.
Multidimensional, multicontrast, spatial frequency modulation imaging with built-in femtosecond pulse characterization and dispersion compensation is presented. We present wavelength domain imaging which produces one-dimensional imaging with single element detection, and a multiplexed spatial and wavelength domain system that produces two-dimensional images and is compatible with single element detection imaging.
Recently we have demonstrated that spatial frequency modulation imaging can use extended excitation sources in linear and nonlinear image modalities, is compatible with single element detection, and results in enhanced lateral resolution across the excitation beam. In this paper, we will present new methods where the SPIFI platform goes from one-dimensional to two-dimensional imaging while still exhibiting the enhanced resolution across the added dimension. Significantly, we present the physical mechanism responsible for the resolution enhancement for all imaging modalities, we provide computational models that support the physical model for the increased resolution, and finally, present experimental verification of the resolution enhancement.
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