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27 October 2014 Optimal timing of retinal scanning during dark adaptation, in the presence of fixation on a target: the role of pupil size dynamics
Boris I. Gramatikov, Kristina Irsch, David Guyton
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Journal of Biomedical Optics, Vol. 19, Issue 10, 106014 (October 2014). https://doi.org/10.1117/1.JBO.19.10.106014
Abstract
While validating our newly developed vision screener based on a double-pass retinal scanning system, we noticed that in all patients the signals from the retina were significantly higher when measurements were performed within a certain time interval referenced to the initial moment when the lights were dimmed and the test subject was asked to fixate on a target. This appeared to be most likely attributable to pupil size dynamics and triggered the present study, whose aim was to assess the pupillary “lights-off” response while fixating on a target in the presence of an accommodative effort. We found that pupil size increases in the first 60 to 70 s after turning off the room lights, and then it decreases toward the baseline in an exponential decay. Our results suggest that there is an optimal time window during which pupil size is expected to be maximal, that is during the second minute after dimming the room lights. During this time, window retinal diagnostic instruments based on double-pass measurement technology should deliver an optimal signal-to-noise ratio. We also propose a mathematical model that can be used to approximate the behavior of the normalized pupil size.
CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
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Boris I. Gramatikov, Kristina Irsch, and David Guyton "Optimal timing of retinal scanning during dark adaptation, in the presence of fixation on a target: the role of pupil size dynamics," Journal of Biomedical Optics 19(10), 106014 (27 October 2014). https://doi.org/10.1117/1.JBO.19.10.106014
Published: 27 October 2014
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Cited by 8 scholarly publications.
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KEYWORDS
Retinal scanning
Eye
Retina
Signal to noise ratio
Video
Compact discs
Diagnostics
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