Towards volume imaging of neurons using quantum diamond microscope

Kasturi Saha

doi:10.1117/12.3004879

13 March 2024 Towards volume imaging of neurons using quantum diamond microscope

Kasturi Saha

Proceedings Volume PC12863, Quantum Effects and Measurement Techniques in Biology and Biophotonics; PC128630J (2024) https://doi.org/10.1117/12.3004879
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Quantum diamond microscopy (QDM) is a technique for wide field-of-view diffraction-limited imaging of a thin and dense layer of negatively charged nitrogen-vacancy (NV) defects in engineered diamond crystals. In the recent past, QDM has enabled imaging of a diverse class of samples with microscopic magnetic field profiles, for example, biological cells with magnetic nanoparticles and current flow profiles in thin quantum materials. A challenging extension of the technique is to perform spatially resolved magnetic field imaging from in-vitro 2D or 3D cultures of mammalian neurons. This potential development can lead to an alternative magnetometry-based neuronal imaging technique, with advantages over conventional scattering-limited multi-photon in-vivo calcium imaging.In this talk I will describe our path toward volume imaging of neurons with QDM.

Conference Presentation

Citation Download Citation

Kasturi Saha "Towards volume imaging of neurons using quantum diamond microscope", Proc. SPIE PC12863, Quantum Effects and Measurement Techniques in Biology and Biophotonics, PC128630J (13 March 2024); https://doi.org/10.1117/12.3004879

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