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The accuracy of optical coherence tomography angiography (OCTA) based blood flow velocimetry is affected by Axial Velocity Gradient (AVG) when the scanning beam is not perpendicular to the blood flow. We have developed two methods to eliminate the effect of AVG on amplitude decorrelation, where the AVG term is cancelled according to the established analytical model of dynamic light scattering (DLS) using two OCTA signals acquired with different spatial resolutions. We verified both solutions with flow phantom experiments. The effectiveness and limitations of both methods are discussed.
(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.
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Zhengyang Xu, Yukun Wang, Xi Chen, Kan Lin, Linbo Liu, "Dual-resolution axial velocity gradient elimination," Proc. SPIE PC12841, Dynamics and Fluctuations in Biomedical Photonics XXI, PC128410N (13 March 2024); https://doi.org/10.1117/12.3005210