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17 March 2023 Sensor for non-invasive detection of SARS-CoV-2 at an early stage of infection
Joanna Jankowska-Śliwińska, Kamil Kosiel, Maciej Kozubal, Anna Szerling, Krzysztof Zaraska, Krzysztof Grabczewski, Piotr Polak, Renata Kruszka, Laura Stanco, Anna Niedzwiecka, Antonina Naskalska, Agnieszka Dabrowska, Krzysztof Pyrc
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Proceedings Volume PC12430, Quantum Sensing and Nano Electronics and Photonics XIX; PC1243014 (2023) https://doi.org/10.1117/12.2650124
Event: SPIE OPTO, 2023, San Francisco, California, United States
Abstract
Fast and non-invasive screening test based on electrochemical detection of structural proteins of SARS-CoV-2 was developed. The measurement being the basis of the test is carried out in a standard three-electrode system, in which the working electrode is covered by bioreceptors immobilized on its surface by durable covalent bonding, ensuring specificity of the detection of desired analyte present in the sample. The carried out measurements allowed for detection of given protein of SARS-CoV-2 in standardized buffered samples and in samples containing virus-like particles. The estimated detection limit of the biosensor does not exceed 10^5 copies of the virus per milliliter.
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Joanna Jankowska-Śliwińska, Kamil Kosiel, Maciej Kozubal, Anna Szerling, Krzysztof Zaraska, Krzysztof Grabczewski, Piotr Polak, Renata Kruszka, Laura Stanco, Anna Niedzwiecka, Antonina Naskalska, Agnieszka Dabrowska, and Krzysztof Pyrc "Sensor for non-invasive detection of SARS-CoV-2 at an early stage of infection", Proc. SPIE PC12430, Quantum Sensing and Nano Electronics and Photonics XIX, PC1243014 (17 March 2023); https://doi.org/10.1117/12.2650124
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KEYWORDS
Sensors
Proteins
Electrodes
Biological research
Biosensors
Particles
Pathogens
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