Multifunctional biocompatible nanoplatforms for near infrared cancer theranostics (Conference Presentation)

Tymish Y. Ohulchanskyy

doi:10.1117/12.2653118

17 March 2023 Multifunctional biocompatible nanoplatforms for near infrared cancer theranostics (Conference Presentation)

Tymish Y. Ohulchanskyy

Author Affiliations +

Proceedings Volume PC12398, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications XIV; PC1239809 (2023) https://doi.org/10.1117/12.2653118
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

The talk will present our recent results on development of multifunctional biocompatible nanoplatforms for cancer theranostics. The three nanoplatforms targeting tumors include polymeric nanoparticles (PNPs), nanoliposomes and protein nanocrystals; they can be equipped with NIR luminescence, photoacoustic (PA) and computed tomography (CT) imaging contrasts, along with PDT/PTT and chemotherapy modalities, which can be selectively activated by tumor microenvironment (TME). The talk will also demonstrate application of PNPs for visible or NIR fluorescence labeling of the systemically injected mesenchymal stem cells, which manifest tumor tropism in metastatic cancer animal model, allowing for fluorescence imaging based detection of primary tumor and metastases.

Conference Presentation

Citation Download Citation

Tymish Y. Ohulchanskyy "Multifunctional biocompatible nanoplatforms for near infrared cancer theranostics (Conference Presentation)", Proc. SPIE PC12398, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications XIV, PC1239809 (17 March 2023); https://doi.org/10.1117/12.2653118

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