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We previously demonstrated that temporarily induced bubbles in ultrasound energy can be used to increase the penetration of light into biological tissue by acting as an optical scattering agent in the biological tissue. In this paper, we study the effect of light fluence on the bubble concentration in the bubble cloud region using monte carlo simulation and tissue mimicking phantom. As a result, we found that optical scattering increased and the fluctuation in the light intensity became stronger as the bubble concentration decrease.
Haemin Kim,Jinwoo Kim, andJin Ho Chang
"Evaluation of light beam distribution according to concentration of ultrasound-induced gas bubbles", Proc. SPIE PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023, PC1237925 (27 March 2023); https://doi.org/10.1117/12.2651064
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Haemin Kim, Jinwoo Kim, Jin Ho Chang, "Evaluation of light beam distribution according to concentration of ultrasound-induced gas bubbles," Proc. SPIE PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023, PC1237925 (27 March 2023); https://doi.org/10.1117/12.2651064