CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume PC12379 > Article
Presentation
9 March 2023 Virtual histology with total-absorption photoacoustic remote sensing microscopy (Conference Presentation)
Benjamin R. Ecclestone, James Tweel, Marian Boktor, Krystal Li, Lixin Chu, Hager Gaouda, Kevan Bell, Deepak Dinakaran, John Mackey, Parsin Haji Reza
Author Affiliations +
Proceedings Volume PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023; PC123791W (2023) https://doi.org/10.1117/12.2650986
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
An automated label-free virtual histology microscope using Photoacoustic Remote Sensing (PARS) microscopy is presented. This device features an optimized architecture providing additional contrasts, and enhancements in image quality and SNR over previous PARS virtual histology embodiments. Concurrently, developments in software and signal processing enable automated scanning of tissue specimens within minutes. Finally, AI-based virtual staining facilitates visualizations analogous to current histochemical staining. The diagnostic utility is demonstrated in unprocessed human tissues. Results validated through clinical efficacy studies demonstrate comparable contrast and diagnostic quality to gold standard histological preparations. This represents a significant step towards a clinical system for virtual pathology.
Conference Presentation
© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Benjamin R. Ecclestone, James Tweel, Marian Boktor, Krystal Li, Lixin Chu, Hager Gaouda, Kevan Bell, Deepak Dinakaran, John Mackey, and Parsin Haji Reza "Virtual histology with total-absorption photoacoustic remote sensing microscopy (Conference Presentation)", Proc. SPIE PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023, PC123791W (9 March 2023); https://doi.org/10.1117/12.2650986
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Tissues
Microscopy
Photoacoustic spectroscopy
Remote sensing
Diagnostics
Software development
Tissue optics
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top