CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume PC12379 > Article
Presentation
9 March 2023 Toward automated deep learning-based virtual histological staining of slide-free total absorption photoacoustic remote sensing (TA-PARS)
Marian Boktor, Benjamin R. Ecclestone, Vlad Pekar, Deepak Dinakaran, John R. Mackey, Paul Fieguth, Parsin Haji Reza
Author Affiliations +
Proceedings Volume PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023; PC123791I (2023) https://doi.org/10.1117/12.2650307
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
Significant efforts are being made to reduce histology turnaround times. Total-Absorption Photoacoustic Remote Sensing (TA-PARS) is the first independent all-optical, label-free optical microscope to provide radiative and non-radiative absorption and optical scattering in a single acquisition. Such array of contrasts enables TA-PARS to rapidly capture most diagnostic elements. Here, a deep learning model, Pix2Pix, is trained within an end-to-end virtual staining framework, utilizing such contrasts. Virtually stained thin and fresh tissue exhibit high concordance when compared against histochemical staining. The proposed work paves the way for developing TA-PARS slide-free histology, which may revolutionize intraoperative microscopic diagnosis and margin assessment.
Conference Presentation
© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Marian Boktor, Benjamin R. Ecclestone, Vlad Pekar, Deepak Dinakaran, John R. Mackey, Paul Fieguth, and Parsin Haji Reza "Toward automated deep learning-based virtual histological staining of slide-free total absorption photoacoustic remote sensing (TA-PARS)", Proc. SPIE PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023, PC123791I (9 March 2023); https://doi.org/10.1117/12.2650307
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Absorption
Photoacoustic spectroscopy
Remote sensing
Tissues
Optical microscopes
Chemical elements
Gold
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top