Presentation
9 March 2023 Multi-parametric characterization of fatty liver disease with Transmission-Reflection Optoacoustic Ultrasound (TROPUS) computed tomography
Author Affiliations +
Abstract
Non-alcoholic fatty liver disease (NAFLD) starts with the accumulation of lipids in liver tissues before progressing into liver cirrhosis and hepatocellular carcinoma. Transmission-reflection optoacoustic ultrasound (TROPUS) can simultaneously interrogate biological tissues with three ultrasound-based imaging modalities based on different contrast mechanisms. We propose TROPUS imaging for the assessment of NAFLD in vivo and ex vivo. Multispectral optoacoustic tomography resolves the oxy- and deoxy-hemoglobin, lipid and melanin content in the tissues. Reflection ultrasound computed tomography facilitates segmenting the liver by providing anatomical information. Transmission ultrasound computed tomography quantifies changes in speed of sound due to lipid accumulation.
Conference Presentation
© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Berkan Lafci, Anna Hadjihambi, Christos Konstantinou, Joaquin L. Herraiz, Neal C. Burton, Xosé Luís Deán-Ben, and Daniel Razansky "Multi-parametric characterization of fatty liver disease with Transmission-Reflection Optoacoustic Ultrasound (TROPUS) computed tomography", Proc. SPIE PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023, PC123790U (9 March 2023); https://doi.org/10.1117/12.2650704
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KEYWORDS
Liver

Computed tomography

Ultrasonography

Optoacoustics

Tissues

Absorption

In vivo imaging

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