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We previously introduced Photo-Magnetic Imaging (PMI) as a true multi-modality imaging technique for non-invasive, high resolution optical tomography. With a simple add-on of continuous wave lasers to an existing MRI system, PMI converts the laser induced temperature increase measured by MR thermometry into tissue optical absorption map utilizing a dedicated Finite Element Model (FEM) based image reconstruction algorithm. The newly implemented multi-wavelength capabilities allow PMI to recover 3D tissue oxygenation maps as well as exogenous contrast agent distribution such as indocyanine green or gold nanoparticles with high-resolution and quantitative accuracy.
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