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Traditionally, line scan OCT (LS-OCT) systems use a cylindrical lens to generate a line-shaped beam with Gaussian intensity illumination along the line, which leads to spatially-dependent signal-to-noise ratio (SNR) distribution of the OCT system along the B-scan direction. A novel, Powell lens-based LS-OCT (PL-LS-OCT) system was designed for uniform intensity illumination along the B-scan direction. The PL-LS-OCT can generate images with ~ 2 μm × 1.7 μm (lateral × axial) resolution in free space at image acquisition rate of and 4,500 fps. Images of biological tissues were acquired with the PL-LS-OCT system.
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