PathCAM: Pathology Computer Assisted Microscope for multiscale expert-in-the-loop digital pathology

J. Quincy Brown; Kimberly L. Ashman; Max Cooper; Huimin Zhuge; Sharon E. Fox; Jonathan I. Epstein; Carola Wenk; Brian Summa

doi:10.1117/12.2658961

17 March 2023 PathCAM: Pathology Computer Assisted Microscope for multiscale expert-in-the-loop digital pathology

J. Quincy Brown, Kimberly L. Ashman, Max Cooper, Huimin Zhuge, Sharon E. Fox, Jonathan I. Epstein, Carola Wenk, Brian Summa

Author Affiliations +

Proceedings Volume PC12363, Multiscale Imaging and Spectroscopy IV; PC1236308 (2023) https://doi.org/10.1117/12.2658961
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Advances in computational image analysis and machine learning in the field of digital pathology seem poised to make transformational changes in disease diagnosis and prognosis, yet currently 99% of all histopathology slides generated in clinical practice are never digitized. We seek to incorporate digital imaging into the standard glass-slide clinical pathology workflow using relatively inexpensive modifications to traditional clinical microscopes. Here we will introduce PathCAM, a pathology computer-assisted microscope for "ambient" digitization of histology slides during the standard pathology workflow. PathCAM leverages high-frequency spatiotemporal sampling and human-machine interaction to deliver complete and accurate digital records of clinical glass-slide analysis. We will discuss the development of the PathCAM system and technical approach, and demonstrate the unique datasets and capabilities afforded by this hybrid digital-analog pathology imaging and analysis platform.

Conference Presentation

Citation Download Citation

J. Quincy Brown, Kimberly L. Ashman, Max Cooper, Huimin Zhuge, Sharon E. Fox, Jonathan I. Epstein, Carola Wenk, and Brian Summa "PathCAM: Pathology Computer Assisted Microscope for multiscale expert-in-the-loop digital pathology", Proc. SPIE PC12363, Multiscale Imaging and Spectroscopy IV, PC1236308 (17 March 2023); https://doi.org/10.1117/12.2658961

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
PRESENTATION

WATCH
PRESENTATION SAVE TO MY LIBRARY

GET CITATION

KEYWORDS

Pathology

Microscopes

Imaging systems

Digital imaging

Image analysis

Machine learning

Keywords/Phrases

Search In:

Publication Years