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2 March 2022 Non-invasive chemically-selective Raman signal enhancement in a scattering medium
Bingxin Tian, Bernhard Rauer, Antoine Boniface, Sylvain Gigan, Hilton Barbosa de Aguiar
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Proceedings Volume PC11969, Adaptive Optics and Wavefront Control for Biological Systems VIII; PC1196906 (2022) https://doi.org/10.1117/12.2610087
Event: SPIE BiOS, 2022, San Francisco, California, United States
Abstract
Deep Raman imaging in complex media has been elusive, due to scattering of the excitation light. Here, we exploit non-invasive wavefront shaping methods using a spectrally resolved speckle variance optimization algorithm in order to enhance the spontaneous Raman signals of a single particle. We demonstrate unprecedented signal enhancement (>5x) in a non-invasive manner for an epi geometry.
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Bingxin Tian, Bernhard Rauer, Antoine Boniface, Sylvain Gigan, and Hilton Barbosa de Aguiar "Non-invasive chemically-selective Raman signal enhancement in a scattering medium", Proc. SPIE PC11969, Adaptive Optics and Wavefront Control for Biological Systems VIII, PC1196906 (2 March 2022); https://doi.org/10.1117/12.2610087
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KEYWORDS
Raman spectroscopy
Raman scattering
Scattering
Wavefronts
Light scattering
Microscopy
Speckle
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