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Currently, electrical stimulation (ES) is used during intraoperative nerve monitoring (IONM) to detect the onset of nerve damage but suffers from current spread making results more uncertain. Infrared neural stimulation (INS) is more spatially precise than ES and has the potential to improve nerve damage detection. Here, we compare ES and INS for IONM in an in vivo animal model. INS and ES had comparable specificities, but INS exhibited a higher sensitivity than ES for less severe forms of damage. These results provide a foundation for using INS in IONM procedures and insight into future clinical translation.
Graham A. Throckmorton,E. Duco Jansen, andAnita Mahadevan-Jansen
"Comparing electrical and infrared neural stimulation for intraoperative nerve monitoring", Proc. SPIE PC11947, Optogenetics and Optical Manipulation 2022, PC1194702 (7 March 2022); https://doi.org/10.1117/12.2607512
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Graham A. Throckmorton, E. Duco Jansen, Anita Mahadevan-Jansen, "Comparing electrical and infrared neural stimulation for intraoperative nerve monitoring," Proc. SPIE PC11947, Optogenetics and Optical Manipulation 2022, PC1194702 (7 March 2022); https://doi.org/10.1117/12.2607512