Although optical coherence tomography has explored coherent volumetric contrast extensively, the access of volumetric incoherent contrast in the human eye has been challenging. To exploit incoherent contrast in human retina in 3D, a confocal oblique scanning laser ophthalmoscopy (CoSLO) is proposed. It is the first time that the incoherent cross-sectional images of the human retina are obtained directly through optical imaging. By utilizing scanned light sheet, depth signals are acquired in parallel, allowing feasible volumetric imaging speed for human retina imaging. With the capability of imaging incoherent scattering contrast in 3D, the CoSLO revealed unique human retina features in 3D.
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