Assessing the elasticity change of cataract lens with OCE

Chen Wu; Chih-Hao Liu; Raksha Raghunathan; Manmohan Singh; Jiasong Li; Zhaolong Han; Kirill V. Larin

doi:10.1117/12.2209141

4 March 2016 Assessing the elasticity change of cataract lens with OCE

Chen Wu, Chih-Hao Liu, Raksha Raghunathan, Manmohan Singh, Jiasong Li, Zhaolong Han, Kirill V. Larin

Proceedings Volume 9693, Ophthalmic Technologies XXVI; 96931P (2016) https://doi.org/10.1117/12.2209141
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

Cataract is one of the most common degenerative diseases that causes blindness. Careful quantification of lens biomechanical properties can greatly assist in early detection of the disease as well as personalization of treatment procedures. In this study, we utilize a phase-sensitive optical coherence elastography (OCE) system to assess the effects of the cold cataract on the biomechanical properties of porcine crystalline lens in vitro. Relaxation rates of air puff induced elastic waves were measured on the same crystalline lens with and without cold cataract. Results demonstrate that the relaxation rate and, thus, associated elasticity of the porcine lens, increased due to the presence of cold cataract.

Citation Download Citation

Chen Wu, Chih-Hao Liu, Raksha Raghunathan, Manmohan Singh, Jiasong Li, Zhaolong Han, and Kirill V. Larin "Assessing the elasticity change of cataract lens with OCE", Proc. SPIE 9693, Ophthalmic Technologies XXVI, 96931P (4 March 2016); https://doi.org/10.1117/12.2209141

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KEYWORDS

Crystals

Elastography

Proteins

Optical coherence tomography

Coherence (optics)

Crystallography

Tissues

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