New insights into photodynamic therapy treatment through the use of 3D Monte Carlo radiation transfer modelling

C. Louis Campbell; Kenneth Wood; C. Tom A. Brown; Harry Moseley

doi:10.1117/12.2212240

29 February 2016 New insights into photodynamic therapy treatment through the use of 3D Monte Carlo radiation transfer modelling

C. Louis Campbell, Kenneth Wood, C. Tom A. Brown, Harry Moseley

Author Affiliations +

Proceedings Volume 9689, Photonic Therapeutics and Diagnostics XII; 96890Q (2016) https://doi.org/10.1117/12.2212240
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

Photodynamic therapy (PDT) has been theoretically investigated using a Monte Carlo radiation transfer (MCRT) model. By including complex three dimensional (3D) tumour models a more appropriate representation of the treatment was achieved. The 3D clustered tumour model was compared to a smooth model, resulting in a significantly deeper penetration associated with the clustered model. The results from the work presented here indicates that light might penetrate deeper than suggested by 2D or simple layered models.

Conference Presentation

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C. Louis Campbell, Kenneth Wood, C. Tom A. Brown, and Harry Moseley "New insights into photodynamic therapy treatment through the use of 3D Monte Carlo radiation transfer modelling", Proc. SPIE 9689, Photonic Therapeutics and Diagnostics XII, 96890Q (29 February 2016); https://doi.org/10.1117/12.2212240

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