Respiratory motion variations from skin surface on lung cancer patients from 4D CT data

Nicolas Gallego-Ortiz; Jonathan Orban de Xivry; Antonin Descampe; Samuel Goossens; Xavier Geets; Guillaume Janssens; Benoit Macq

doi:10.1117/12.2043477

21 March 2014 Respiratory motion variations from skin surface on lung cancer patients from 4D CT data

Nicolas Gallego-Ortiz, Jonathan Orban de Xivry, Antonin Descampe, Samuel Goossens, Xavier Geets, Guillaume Janssens, Benoit Macq

Author Affiliations +

Proceedings Volume 9034, Medical Imaging 2014: Image Processing; 90342Y (2014) https://doi.org/10.1117/12.2043477
Event: SPIE Medical Imaging, 2014, San Diego, California, United States

Abstract

In radiation therapy of thorax and abdomen regions, knowing how respiratory motion modifies tumor position and trajectory is crucial for accurate dose delivery to tumors while avoiding healthy tissue and organs at risk. Three types of variations are studied: motion amplitudes measured from the patient's skin surface and internal tumor trajectory, internal/external correlations and tumor trajectory baseline shift. Four male patients with lung cancer with three repeated 4D computed tomography (4DCT) scans, taken on different treatment days, were studied. Surfaces were extracted from 4DCT scans by segmentation. Motion over specific regions of interest was analyzed with respect to the motion of the tumor center of mass and correlation coefficient was computed. Tumor baseline shifts were analyzed after rigid registration based on vertebrae and surface registration. External amplitude variations were observed between fractions. Correlation coefficients of internal trajectories and external distances are greater than 0.6 in the abdomen. This correlation was observable and significant for all patients showing that the external motion is a good surrogate for internal movement on an intra-fraction basis. However for the inter-fraction case, external amplitude variations were observed between fractions and no correlation was found with the internal amplitude variations. Moreover, baseline shifts after surface registration were greater than those after vertebrae registration and the mean distance between surfaces after registration was not correlated to the magnitude of the baseline shift. These two observations show that, with the current representation of the external surface, inter-fraction variations are not detectable on the surface.

Citation Download Citation

Nicolas Gallego-Ortiz, Jonathan Orban de Xivry, Antonin Descampe, Samuel Goossens, Xavier Geets, Guillaume Janssens, and Benoit Macq "Respiratory motion variations from skin surface on lung cancer patients from 4D CT data", Proc. SPIE 9034, Medical Imaging 2014: Image Processing, 90342Y (21 March 2014); https://doi.org/10.1117/12.2043477

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
6 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Tumors

Image registration

Skin

Lung cancer

Abdomen

Rigid registration

4D CT imaging

Show All Keywords

Keywords/Phrases

Search In:

Publication Years