A demonstration of multiplex biosensing using whispering gallery mode microspheres positioned onto a microstructured optical fiber tip

T. Reynolds; A. François; S. J. Nicholls; T. M. Monro

doi:10.1117/12.2039328

28 February 2014 A demonstration of multiplex biosensing using whispering gallery mode microspheres positioned onto a microstructured optical fiber tip

T. Reynolds, A. François, S. J. Nicholls, T. M. Monro

Author Affiliations +

Proceedings Volume 8951, Optical Diagnostics and Sensing XIV: Toward Point-of-Care Diagnostics; 895110 (2014) https://doi.org/10.1117/12.2039328
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

Here, we show that multiplexed Whispering Gallery Modes sensing can be achieved using two dye-doped microspheres positioned onto the tip of a Microstructured Optical Fiber. By operating the dye-doped microspheres below their lasing threshold, the individual resonances of each sphere overlap and therefore cannot be distinguished. However, when excited above their lasing threshold results in a de-convoluted spectrum where the resonances belonging to the individual spheres can be determined, enabling the detection of a specific interaction in one resonator and using the second as a dynamic reference, or monitoring different specific interactions with both spheres.

Citation Download Citation

T. Reynolds, A. François, S. J. Nicholls, and T. M. Monro "A demonstration of multiplex biosensing using whispering gallery mode microspheres positioned onto a microstructured optical fiber tip ", Proc. SPIE 8951, Optical Diagnostics and Sensing XIV: Toward Point-of-Care Diagnostics, 895110 (28 February 2014); https://doi.org/10.1117/12.2039328

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