A consecutive reconstruction strategy for estimating absorption and scattering coefficient distribution in multiple-illumination photoacoustic tomography (MIPAT)

Peng Shao; Tyler J. Harrison; Roger J. Zemp

doi:10.1117/12.2040671

3 March 2014 A consecutive reconstruction strategy for estimating absorption and scattering coefficient distribution in multiple-illumination photoacoustic tomography (MIPAT)

Peng Shao, Tyler J. Harrison, Roger J. Zemp

Author Affiliations +

Proceedings Volume 8943, Photons Plus Ultrasound: Imaging and Sensing 2014; 89433U (2014) https://doi.org/10.1117/12.2040671
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

Quantitative photoacoustic microscopy (qPAT) is challenging. We present an algorithm which consecutively reconstructs absorption and scattering coefficient distributions with an iterative scheme in multiple-illumination photoacoustic tomography (MIPAT). In each iteration, the absorption distribution is estimated with the least-squares fixed-point iteration method. Then the diffusion coefficient is estimated with an updated version of optical fluence based on the previously modified absorption information. This procedure is repeated till an acceptable results is achieved. Simulation examples demonstrate the capability of this method in faithfully recovering the absorption and diffusion coeffient distributions, and fast convergence.

Citation Download Citation

Peng Shao, Tyler J. Harrison, and Roger J. Zemp "A consecutive reconstruction strategy for estimating absorption and scattering coefficient distribution in multiple-illumination photoacoustic tomography (MIPAT)", Proc. SPIE 8943, Photons Plus Ultrasound: Imaging and Sensing 2014, 89433U (3 March 2014); https://doi.org/10.1117/12.2040671

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