Photoacoustic imaging of prostate brachytherapy seeds with transurethral light delivery

Muyinatu A. Lediju Bell; Xiaoyu Guo; Danny Y. Song; Emad M. Boctor

doi:10.1117/12.2040751

3 March 2014 Photoacoustic imaging of prostate brachytherapy seeds with transurethral light delivery

Muyinatu A. Lediju Bell, Xiaoyu Guo, Danny Y. Song, Emad M. Boctor

Proceedings Volume 8943, Photons Plus Ultrasound: Imaging and Sensing 2014; 89430N (2014) https://doi.org/10.1117/12.2040751
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

We present a novel approach to photoacoustic imaging of prostate brachytherapy seeds utilizing an existing urinary catheter for transurethral light delivery. Two canine prostates were surgically implanted with brachyther- apy seeds under transrectal ultrasound guidance. One prostate was excised shortly after euthanasia and fixed in gelatin. The second prostate was imaged in the native tissue environment shortly after euthanasia. A urinary catheter was inserted in the urethra of each prostate. A 1-mm core diameter optical fiber coupled to a 1064 nm Nd:YAG laser was inserted into the urinary catheter. Light from the fiber was either directed mostly parallel to the fiber axis (i.e. end-fire fire) or mostly 90° to the fiber axis (i.e. side-fire fiber). An Ultrasonix SonixTouch scanner, transrectal ultrasound probe with curvilinear (BPC8-4) and linear (BPL9-5) arrays, and DAQ unit were utilized for synchronized laser light emission and photoacoustic signal acquisition. The implanted brachytherapy seeds were visualized at radial distances of 6-16 mm from the catheter. Multiple brachytherapy seeds were si- multaneously visualized with each array of the transrectal probe using both delay-and-sum (DAS) and short-lag spatial coherence (SLSC) beamforming. This work is the first to demonstrate the feasibility of photoacoustic imaging of prostate brachytherapy seeds using a transurethral light delivery method.

Citation Download Citation

Muyinatu A. Lediju Bell, Xiaoyu Guo, Danny Y. Song, and Emad M. Boctor "Photoacoustic imaging of prostate brachytherapy seeds with transurethral light delivery", Proc. SPIE 8943, Photons Plus Ultrasound: Imaging and Sensing 2014, 89430N (3 March 2014); https://doi.org/10.1117/12.2040751

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available