Simulation of light transport in arthritic- and non-arthritic human fingers

Matija Milanic; Lukasz A. Paluchowski; Lise Lyngsnes Randeberg

doi:10.1117/12.2035979

4 March 2014 Simulation of light transport in arthritic- and non-arthritic human fingers

Matija Milanic, Lukasz A. Paluchowski, Lise Lyngsnes Randeberg

Proceedings Volume 8936, Design and Quality for Biomedical Technologies VII; 893602 (2014) https://doi.org/10.1117/12.2035979
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

Rheumatoid arthritis is a disease that frequently leads to joint destruction. It has high incidence rates worldwide, and the disease significantly reduces patient’s quality of life due to pain, swelling and stiffness of the affected joints. Early diagnosis is necessary to improve course of the disease, therefore sensitive and accurate diagnostic tools are required. Optical imaging techniques have capability for early diagnosis and monitoring of arthritis. As compared to conventional diagnostic techniques optical technique is a noninvasive, noncontact and fast way of collecting diagnostic information. However, a realistic model of light transport in human joints is needed for understanding and developing of such optical diagnostic tools. The aim of this study is to develop a 3D numerical model of light transport in a human finger. The model will guide development of a hyperspectral imaging (HSI) diagnostic modality for arthritis in human fingers. The implemented human finger geometry is based on anatomical data. Optical data of finger tissues are adjusted to represent either an arthritic or an unaffected finger. The geometry and optical data serve as input into a 3D Monte Carlo method, which calculate diffuse reflectance, transmittance and absorbed energy distributions. The parameters of the model are optimized based on HIS-measurements of human fingers. The presented model serves as an important tool for understanding and development of HSI as an arthritis diagnostic modality. Yet, it can be applied to other optical techniques and finger diseases.

Citation Download Citation

Matija Milanic, Lukasz A. Paluchowski, and Lise Lyngsnes Randeberg "Simulation of light transport in arthritic- and non-arthritic human fingers", Proc. SPIE 8936, Design and Quality for Biomedical Technologies VII, 893602 (4 March 2014); https://doi.org/10.1117/12.2035979

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