In vivo functional imaging of embryonic chick heart using ultrafast 1310nm-band spectral domain optical coherence tomography

Peng Li; Xin Yin; Ruikang K. Wang

doi:10.1117/12.2004773

26 March 2013 In vivo functional imaging of embryonic chick heart using ultrafast 1310nm-band spectral domain optical coherence tomography

Peng Li, Xin Yin, Ruikang K. Wang

Author Affiliations +

Proceedings Volume 8593, Optical Methods in Developmental Biology; 859304 (2013) https://doi.org/10.1117/12.2004773
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

During the cardiac development, the cardiac wall and the blood flow actively interact with each other, and determine the biomechanical environment to which the embryonic heart exposes. Employing an ultrafast 1310nm-band dual-camera spectral domain optical coherence tomography (SDOCT), the radial strain rate of the myocardial wall can be extracted with high signal-to-noise ratio, at the same time the Doppler velocity of the blood flow can also be displayed. The ability to simultaneously characterize these two cardiac tissues provides a powerful approach to better understand the interaction between the cardiac wall and the blood flow, which is important to the investigation of cardiac development.

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Peng Li, Xin Yin, and Ruikang K. Wang "In vivo functional imaging of embryonic chick heart using ultrafast 1310nm-band spectral domain optical coherence tomography", Proc. SPIE 8593, Optical Methods in Developmental Biology, 859304 (26 March 2013); https://doi.org/10.1117/12.2004773

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KEYWORDS

Heart

Blood circulation

Optical coherence tomography

Doppler effect

Phase shifts

Ultrafast imaging

Tissues

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