Paper
2 March 2012 A liquid xenon detector for PET applications: simulated performance
A. Miceli, A. Andreyev, D. Bryman, J. Glister, L. Kurchaninov, A. Muennich, F. Retiere, V. Sossi
Author Affiliations +
Abstract
We are investigating a liquid xenon (LXe) gamma ray detector-based PET system for small animals. The proposed system consists of 12 modules arranged into a ring. Each detector module is a trapezoidal LXe time projection chamber (TPC) viewed by two arrays of large area avalanche photodiodes (LAAPD). We developed a Geant4-based Monte Carlo code to model the LXe PET system and study its imaging performance. Events depositing energy in multiple locations were reconstructed with a Compton reconstruction algorithm. The simulated data were stored in a list-mode file and reconstructed with the maximum likelihood expectation maximization iterative algorithm (MLEM). Simulation results indicate an absolute sensitivity at the center of the field of view (FOV) of 12.6% and a 3D position resolution ≤ 0.8 mm (FWHM) throughout the FOV. A simulated image of a micro-Derenzo phantom shows that rods of 0.6 mm diameter are visible.
© (2012) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
A. Miceli, A. Andreyev, D. Bryman, J. Glister, L. Kurchaninov, A. Muennich, F. Retiere, and V. Sossi "A liquid xenon detector for PET applications: simulated performance", Proc. SPIE 8313, Medical Imaging 2012: Physics of Medical Imaging, 83130V (2 March 2012); https://doi.org/10.1117/12.911662
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KEYWORDS
Monte Carlo methods

Positron emission tomography

Sensors

Reconstruction algorithms

Expectation maximization algorithms

Avalanche photodetectors

Imaging systems

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