Ring-shaped confocal photoacoustic computed tomography for small-animal whole-body imaging

Jun Xia; Muhammad Chatni; Konstantin Maslov; Zijian Guo; Mark Anastasio; Lihong V. Wang

doi:10.1117/12.906056

23 February 2012 Ring-shaped confocal photoacoustic computed tomography for small-animal whole-body imaging

Jun Xia, Muhammad Chatni, Konstantin Maslov, Zijian Guo, Mark Anastasio, Lihong V. Wang

Proceedings Volume 8223, Photons Plus Ultrasound: Imaging and Sensing 2012; 82230G (2012) https://doi.org/10.1117/12.906056
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

We report herein a novel three-dimensional photoacoustic computed tomography (PACT) system for small-animal whole-body imaging. The PACT system, based on a 512-element full-ring ultrasonic transducer array, was cylindrically focused and capable of forming a two-dimensional image in 1.6 seconds. The pulsed laser could either illuminate directly from the top or be reshaped to illuminate the sample from the side. Top illumination was mainly used for mouse brain and mouse embryo imaging. Side illumination provided in vivo anatomical images of an adult mouse. By translating the mouse along the elevational direction, the system provided serial cross-sectional images.

Citation Download Citation

Jun Xia, Muhammad Chatni, Konstantin Maslov, Zijian Guo, Mark Anastasio, and Lihong V. Wang "Ring-shaped confocal photoacoustic computed tomography for small-animal whole-body imaging", Proc. SPIE 8223, Photons Plus Ultrasound: Imaging and Sensing 2012, 82230G (23 February 2012); https://doi.org/10.1117/12.906056

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