Ultrafast laser induced condensation of molecules

Ling Gu; Samarendra K. Mohanty

doi:10.1117/12.875930

10 February 2011 Ultrafast laser induced condensation of molecules

Ling Gu, Samarendra K. Mohanty

Proceedings Volume 7925, Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XI; 792503 (2011) https://doi.org/10.1117/12.875930
Event: SPIE LASE, 2011, San Francisco, California, United States

Abstract

We have found that ultrafast laser microbeam inducing bubble(s) can lead to condensation of molecules in solution. The laser microbeam was generated by coupling a near infrared mode-locked femtosecond (fs) laser beam onto an inverted fluorescence microscope and focusing it with a 100X objective. Fluorescence imaging revealed that collapse of cavitation micro-bubbles created high-concentration regions of dye molecules in the aqueous solution. Further, twophoton excitation of the molecules under the ultrafast laser microbeam showed significant increase in fluorescence intensity as a function of laser exposure time without micro-bubble formation. This may be attributed to nano-bubble formation and or conformational change in the molecules under intense laser intensity at the focused spot to significantly enhance the molar absorptivity (extinction coefficient) or fluorescence excitation cross-section. High-concentration regions of the dye molecules are found to be retained for a longer period of time and therefore provide an opportunity for collection of these condensed molecules using microcapilary and/or for further analysis.

Citation Download Citation

Ling Gu and Samarendra K. Mohanty "Ultrafast laser induced condensation of molecules", Proc. SPIE 7925, Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XI, 792503 (10 February 2011); https://doi.org/10.1117/12.875930

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
6 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Molecules

Luminescence

Molecular lasers

Ultrafast lasers

Femtosecond phenomena

Cavitation

Microscopes

Show All Keywords

Keywords/Phrases

Search In:

Publication Years