Arrhenius parameters for primary thermal injury in human tonsillar tissue

Kathleen McMillan; Rebecca Radabaugh; James E. Coad

doi:10.1117/12.876338

22 February 2011 Arrhenius parameters for primary thermal injury in human tonsillar tissue

Kathleen McMillan, Rebecca Radabaugh, James E. Coad

Proceedings Volume 7901, Energy-based Treatment of Tissue and Assessment VI; 790110 (2011) https://doi.org/10.1117/12.876338
Event: SPIE BiOS, 2011, San Francisco, California, United States

Abstract

Clinical implementation of a thermal therapy requires the ability to predict tissue injury following exposures to specific thermal histories. As part of an effort to develop a nonexcisional alternative to tonsillectomy, the degree of primary hyperthermic tissue injury in human tonsil was characterized. Fifteen fresh pediatric hypertrophic tonsillectomy specimens were sectioned and treated in a NIST-calibrated saline bath at temperatures of 40 to 70°C with hold times of one to seven minutes. The treated tissues were subsequently nitroblue tetrazolium (NBT) stained to assess for thermal respiratory enzyme inactivation as a marker of cellular injury/death. The NBT stains were quantitatively image analyzed and used to calculate Arrhenius parameters for primary thermal injury in human tonsils.

Citation Download Citation

Kathleen McMillan, Rebecca Radabaugh, and James E. Coad "Arrhenius parameters for primary thermal injury in human tonsillar tissue", Proc. SPIE 7901, Energy-based Treatment of Tissue and Assessment VI, 790110 (22 February 2011); https://doi.org/10.1117/12.876338

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
13 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Tissues

Injuries

Image analysis

Matrices

Natural surfaces

RGB color model

Thermal modeling

Show All Keywords

Keywords/Phrases

Search In:

Publication Years