Functional multilayer coated long period grating tuned in transition region for life science applications

P. Pilla; V. Malachovská; A. Borriello; M. Giordano; L. Ambrosio; A. Cutolo; A. Cusano

doi:10.1117/12.866188

8 September 2010 Functional multilayer coated long period grating tuned in transition region for life science applications

P. Pilla, V. Malachovská, A. Borriello, M. Giordano, L. Ambrosio, A. Cutolo, A. Cusano

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Proceedings Volume 7653, Fourth European Workshop on Optical Fibre Sensors; 76531O (2010) https://doi.org/10.1117/12.866188
Event: (EWOFS'10) Fourth European Workshop on Optical Fibre Sensors, 2010, Porto, Portugal

Abstract

We report preliminary results on the development of multilayer coated long period gratings (LPGs) for life science applications. The dip-coating technique and a solvent/nonsolvent strategy were exploited to deposit double-layer polymeric film onto a LPG. A primary coating of atactic polystyrene was used as high refractive index layer to tune the working point of the device in the so-called transition region thus achieving remarkable surrounding medium refractive index sensitivity. A secondary layer of atactic poly(methyl methacrylate-co-methacrylic acid) containing functional carboxyl groups, characterized by a lower refractive index, was deposited onto the primary coating in order to have the desired functional groups on the surface of the device. Commonly used covalent immobilization procedure, NHS/EDC coupling method, was exploited to link streptavidin on the surface of the functionalized coated device. Finally, real-time detection of biotinylated bovine serum albumin affinity binding on immobilized streptavidin was performed by monitoring the shift of the LPG attenuation bands.

Citation Download Citation

P. Pilla, V. Malachovská, A. Borriello, M. Giordano, L. Ambrosio, A. Cutolo, and A. Cusano "Functional multilayer coated long period grating tuned in transition region for life science applications", Proc. SPIE 7653, Fourth European Workshop on Optical Fibre Sensors, 76531O (8 September 2010); https://doi.org/10.1117/12.866188

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KEYWORDS

Signal attenuation

Cladding

Picosecond phenomena

Multilayers

Polymers

Refractive index

Coating

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