Imaging of matrix-disorder in normal and pathological human dermis using nonlinear optical microscopy

Shuangmu Zhuo; Jianxin Chen; Shusen Xie; Liqin Zheng; Xingshan Jiang

doi:10.1117/12.849387

25 November 2009 Imaging of matrix-disorder in normal and pathological human dermis using nonlinear optical microscopy

Shuangmu Zhuo, Jianxin Chen, Shusen Xie, Liqin Zheng, Xingshan Jiang

Proceedings Volume 7634, Optical Sensors and Biophotonics; 763417 (2009) https://doi.org/10.1117/12.849387
Event: Asia Communications and Photonics, 2009, Shanghai, Shanghai , China

Abstract

In dermis, collagen and elastin are important structural proteins of extracellular maxtrix. The matrix-disorder is associated with various physiologic processes, such as localized scleroderma, anetoderma, photoaging. In this work, we demonstrate the capability of nonlinear optical microscopy in imaging structural proteins in normal and pathological human dermis.

Citation Download Citation

Shuangmu Zhuo, Jianxin Chen, Shusen Xie, Liqin Zheng, and Xingshan Jiang "Imaging of matrix-disorder in normal and pathological human dermis using nonlinear optical microscopy", Proc. SPIE 7634, Optical Sensors and Biophotonics, 763417 (25 November 2009); https://doi.org/10.1117/12.849387

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