CMOS modulated light cameras for sensitive surface plasmon resonance imaging

Nicholas S. Johnston; Roger A. Light; Ciaran E. Stewart; Mike G. Somekh; Mark C. Pitter

doi:10.1117/12.843175

16 February 2010 CMOS modulated light cameras for sensitive surface plasmon resonance imaging

Nicholas S. Johnston, Roger A. Light, Ciaran E. Stewart, Mike G. Somekh, Mark C. Pitter

Proceedings Volume 7577, Plasmonics in Biology and Medicine VII; 75770H (2010) https://doi.org/10.1117/12.843175
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

Complementary metal oxide semiconductor (CMOS) cameras that can measure the phase and amplitude of periodically modulated optical signals have been developed. These allow parallel lock-in imaging at up to 256 x 256 pixels resolution without the need for slow and costly mechanical scanning. In conjunction with a differential surface plasmon resonance (dSPR) system, spatially resolved SPR imaging has been achieved with sensitivities of better than 10 microRIU per pixel per second. Results demonstrating the performance of modulated light cameras for dSPR imaging and high resolution SPR microscopy are presented and discussed.

Citation Download Citation

Nicholas S. Johnston, Roger A. Light, Ciaran E. Stewart, Mike G. Somekh, and Mark C. Pitter "CMOS modulated light cameras for sensitive surface plasmon resonance imaging", Proc. SPIE 7577, Plasmonics in Biology and Medicine VII, 75770H (16 February 2010); https://doi.org/10.1117/12.843175

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