An integrated CMOS dual lock-in amplifier for optoelectronic antigens detection

Nam-Pyo Hong; Do-Gyun Kim; In-Il Jung; Ho-Hyun Son; Tae-Kyung Chung; Young-ki Choi; Young-Wan Choi

doi:10.1117/12.841860

26 February 2010 An integrated CMOS dual lock-in amplifier for optoelectronic antigens detection

Nam-Pyo Hong, Do-Gyun Kim, In-Il Jung, Ho-Hyun Son, Tae-Kyung Chung, Young-ki Choi, Young-Wan Choi

Proceedings Volume 7572, Optical Diagnostics and Sensing X: Toward Point-of-Care Diagnostics; 75720J (2010) https://doi.org/10.1117/12.841860
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

We have designed dual lock-in amplifier (LIA) circuits in 0.18 μm CMOS technology for antibody-antigens (IgG) detection using optoelectronics. The purpose of this work is to develop a lock-in amplifier integrated circuit (IC) using the dual phase scheme that detect the phase difference between the input signal and the reference signal although a phase shifter is absent. Our LIA consist of high gain amplifier, signal amplifier, and phase sensitive detection. Amplifier structure is based on two-stage differential operational amplifier (op-amp) with RC Miller compensation technique. By using the RC Miller compensation technique, we obtain 60° the phase margin of the op-amp. Here, the resistor works for increasing the unit gain bandwidth and the capacitor works for increasing the phase margin. The lock-in amplifier consume 8.6 mA from a 1.8 V supply.

Citation Download Citation

Nam-Pyo Hong, Do-Gyun Kim, In-Il Jung, Ho-Hyun Son, Tae-Kyung Chung, Young-ki Choi, and Young-Wan Choi "An integrated CMOS dual lock-in amplifier for optoelectronic antigens detection", Proc. SPIE 7572, Optical Diagnostics and Sensing X: Toward Point-of-Care Diagnostics, 75720J (26 February 2010); https://doi.org/10.1117/12.841860

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