High sensitivity glucose sensor based on optical heterodyne phase detection

Jiun-You Lin; Kun-Huang Chen; Jing-Heng Chen; Yu-Cheng Liao; Yu-Hsien Lin

doi:10.1117/12.834705

24 August 2009 High sensitivity glucose sensor based on optical heterodyne phase detection

Jiun-You Lin, Kun-Huang Chen, Jing-Heng Chen, Yu-Cheng Liao, Yu-Hsien Lin

Proceedings Volume 7381, International Symposium on Photoelectronic Detection and Imaging 2009: Material and Device Technology for Sensors; 738129 (2009) https://doi.org/10.1117/12.834705
Event: International Symposium on Photoelectronic Detection and Imaging 2009, 2009, Beijing, China

Abstract

Measurements of glucose concentration are important parts of biochemical analyses. Based on the principles of the common-path heterodyne interferometry, we develop a high sensitivity optical sensor for measuring glucose concentration. A heterodyne light beam after transmitted through a glucose solution passes through some polarization components for interference. The phase difference determined with heterodyne interferometric technique of the interference signal is greatly enhanced as a result of proper azimuth angles of some polarization components, and a high sensitivity measurement of glucose concentration can be achieved. The feasibility of the measuring method was demonstrated by our experimental results. This optical sensor should bear the merits of high accuracy, short sample medium length, and simpler operational endeavor.

Citation Download Citation

Jiun-You Lin, Kun-Huang Chen, Jing-Heng Chen, Yu-Cheng Liao, and Yu-Hsien Lin "High sensitivity glucose sensor based on optical heterodyne phase detection", Proc. SPIE 7381, International Symposium on Photoelectronic Detection and Imaging 2009: Material and Device Technology for Sensors, 738129 (24 August 2009); https://doi.org/10.1117/12.834705

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