Monitoring of epithelium capillary density

Rajesh Kanawade; Gennadiy Saiko; Alexandre Douplik

doi:10.1117/12.831725

9 July 2009 Monitoring of epithelium capillary density

Rajesh Kanawade, Gennadiy Saiko, Alexandre Douplik

Proceedings Volume 7371, Novel Optical Instrumentation for Biomedical Applications IV; 73711L (2009) https://doi.org/10.1117/12.831725
Event: European Conferences on Biomedical Optics, 2009, Munich, Germany

Abstract

Monitoring the epithelium vessel capillary density pattern is critically important for preventing rapidly developing life threatening syndromes such as shock or systemic organ failures. The objective of this study is real time monitoring of epithelium vessel density pattern. The fiber sensor will be based on spatially resolved diffuse reflectance spectra. The parameters comprising period and depth of capillary spatial modulation are exploited for shock detection. The preliminary investigations with simulated spectra have shown that the new method can reasonably extracts minor deviations of oxygenation and local volume blood fraction - parameters, directly related to the local vessel density. The original method developed to use these parameters is much less dependent on light scattering in visible range as opposed to the most of the currently used methods.

Citation Download Citation

Rajesh Kanawade, Gennadiy Saiko, and Alexandre Douplik "Monitoring of epithelium capillary density", Proc. SPIE 7371, Novel Optical Instrumentation for Biomedical Applications IV, 73711L (9 July 2009); https://doi.org/10.1117/12.831725

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