Multispectral autofluorescence diagnosis of non-melanoma cutaneous tumors

Ekaterina Borisova; Daniela Dogandjiiska; Irina Bliznakova; Latchezar Avramov; Elmira Pavlova; Petranka Troyanova

doi:10.1117/12.831563

7 July 2009 Multispectral autofluorescence diagnosis of non-melanoma cutaneous tumors

Ekaterina Borisova, Daniela Dogandjiiska, Irina Bliznakova, Latchezar Avramov, Elmira Pavlova, Petranka Troyanova

Proceedings Volume 7368, Clinical and Biomedical Spectroscopy; 736823 (2009) https://doi.org/10.1117/12.831563
Event: European Conferences on Biomedical Optics, 2009, Munich, Germany

Abstract

Fluorescent analysis of basal cell carcinoma (BCC), squamous cell carcinoma (SCC), keratoacanthoma and benign cutaneous lesions is carried out under initial phase of clinical trial in the National Oncological Center - Sofia. Excitation sources with maximum of emission at 365, 380, 405, 450 and 630 nm are applied for better differentiation between nonmelanoma malignant cutaneous lesions fluorescence and spectral discrimination from the benign pathologies. Major spectral features are addressed and diagnostic discrimination algorithms based on lesions' emission properties are proposed. The diagnostic algorithms and evaluation procedures found will be applied for development of an optical biopsy clinical system for skin cancer detection in the frames of National Oncological Center and other university hospital dermatological departments in our country.

Citation Download Citation

Ekaterina Borisova, Daniela Dogandjiiska, Irina Bliznakova, Latchezar Avramov, Elmira Pavlova, and Petranka Troyanova "Multispectral autofluorescence diagnosis of non-melanoma cutaneous tumors", Proc. SPIE 7368, Clinical and Biomedical Spectroscopy, 736823 (7 July 2009); https://doi.org/10.1117/12.831563

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