3D structural measurements of the proximal femur from 2D DXA images using a statistical atlas

Omar M. Ahmad; Krishna Ramamurthi; Kevin E. Wilson; Klaus Engelke; Mary Bouxsein; Russell H. Taylor

doi:10.1117/12.811176

27 February 2009 3D structural measurements of the proximal femur from 2D DXA images using a statistical atlas

Omar M. Ahmad, Krishna Ramamurthi, Kevin E. Wilson, Klaus Engelke, Mary Bouxsein, Russell H. Taylor

Proceedings Volume 7260, Medical Imaging 2009: Computer-Aided Diagnosis; 726005 (2009) https://doi.org/10.1117/12.811176
Event: SPIE Medical Imaging, 2009, Lake Buena Vista (Orlando Area), Florida, United States

Abstract

A method to obtain 3D structural measurements of the proximal femur from 2D DXA images and a statistical atlas is presented. A statistical atlas of a proximal femur was created consisting of both 3D shape and volumetric density information and then deformably registered to 2D fan-beam DXA images. After the registration process, a series of 3D structural measurements were taken on QCT-estimates generated by transforming the registered statistical atlas into a voxel volume. These measurements were compared to the equivalent measurements taken on the actual QCT (ground truth) associated with the DXA images for each of 20 human cadaveric femora. The methodology and results are presented to address the potential clinical feasibility of obtaining 3D structural measurements from limited angle DXA scans and a statistical atlas of the proximal femur in-vivo.

Citation Download Citation

Omar M. Ahmad, Krishna Ramamurthi, Kevin E. Wilson, Klaus Engelke, Mary Bouxsein, and Russell H. Taylor "3D structural measurements of the proximal femur from 2D DXA images using a statistical atlas", Proc. SPIE 7260, Medical Imaging 2009: Computer-Aided Diagnosis, 726005 (27 February 2009); https://doi.org/10.1117/12.811176

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