Paper
23 February 2009 Seeing the light: a photonic visual prosthesis for the blind
Patrick Degenaar, Nir Grossman, Brian McGovern, Mark Neil, Emmanuel Drakakis, Konstantin Nikolic
Author Affiliations +
Proceedings Volume 7180, Photons and Neurons; 71800I (2009) https://doi.org/10.1117/12.823577
Event: SPIE BiOS, 2009, San Jose, California, United States
Abstract
This paper highlights how the genetic incorporation of artificial opsins into the retina can lead to a new class of retinal prosthesis. We demonstrate the efficacy of incorporating channelrhodopsin into neuron cells in-vitro and show how that can be scaled to in-vivo. We show that we need typically 100mW/cm2 of instantaneous light intensity on the neuron in order to stimulate action potentials which results in 10W/cm2 required from the light source. We thus use GaN LED arrays to provide spatially controlled stimulation which is of sufficient brightness to stimulate the cells.
© (2009) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Patrick Degenaar, Nir Grossman, Brian McGovern, Mark Neil, Emmanuel Drakakis, and Konstantin Nikolic "Seeing the light: a photonic visual prosthesis for the blind", Proc. SPIE 7180, Photons and Neurons, 71800I (23 February 2009); https://doi.org/10.1117/12.823577
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CITATIONS
Cited by 2 scholarly publications.
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KEYWORDS
Light emitting diodes

Neurons

Gallium nitride

Retina

Action potentials

Ion channels

Photons

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